Carbonell Núñez, Caterina (Date of defense: 2016-12-19)
Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Activation of the p38 SAPK is critical to elicit the early gene ...
Häkkinen, Hanna-Maria (Date of defense: 2022-07-01)
Cellular errors can spontaneously occur during vertebrate embryo development and can lead to apoptosis. Recent work in our lab revealed a novel function of the embryonic epithelium as an efficient ...
Theka, Ilda (Date of defense: 2017-02-06)
Las células madre embrionarias (ESCs) derivan de la masa cellular interna de los blastocistos y son capaces de generar las tres capas germinales. Muchos factores controlan la pluripotencia incluyendo ...
Ferrando Martorell, Eva (Date of defense: 2015-11-10)
The activation of Notch1 receptor triggers differential outcomes depending on the upstream activating ligand. This way, Jag1-Notch1 activation promotes endothelial to hematopoietic transition process ...
Roset i Huguet, Ramon (Date of defense: 2008-04-04)
The aim of this thesis is the characterization of a protein involved in apoptosis. Our group has identified an early step common to different forms of intrinsic apoptosis stimuli. This step requires de ...
Lecland, Nicolas (Date of defense: 2014-04-10)
During mitotic spindle assembly, γ-tubulin ring complexes (γTuRCs) nucleate microtubules at the centrosome, around mitotic chromatin and, by augmindependent recruitment, from pre-existing microtubules. ...
Duran Nebreda, Salvador (Date of defense: 2016-01-19)
En aquesta tesi hem intentat atacar preguntes relacionades amb els orígens de la vida multicel•lular i dels comportaments cooperatius a la nostra biosfera. Particularment hem fet ús de mètodes “no ...
Pezzano, Fabio (Date of defense: 2022-06-13)
Cells commonly live in a crowded environment, in a tissue or in a developing embryo. The extracellular matrix and/or surrounding neighboring cells can impose physical deformations to which cells need ...
Tellechea Recarte, Mónica (Date of defense: 2017-05-19)
Macrophages are exquisite sensors of tissue homeostasis that can rapidly switch between pro- and anti-inflammatory or regulatory modes to respond to perturbations in the microenvironment. This functional ...
Belmonte Mateos, Carla (Date of defense: 2022-02-03)
Precise regulation of neurogenesis is achieved by differentially allocating the neurogenic competence along the tissue. In the hindbrain proneural gene expression is stereotypically confined in segment ...