Jungfleisch, Jennifer (Date of defense: 2015-03-20)
Translation control is a vital aspect of gene expression for both viruses and their cellular hosts. We have previously shown that the cellular mRNA decay activators Dhh1 and Lsm1-7 promote translation ...
Galão, Rui Pedro Ribeiro (Date of defense: 2010-12-01)
By using the ability of the positive-strand RNA ((+)RNA) virus BMV to replicate in yeast it was previously shown that subunits of the LSm1-7 ring, as well as Pat1 and Dhh1 play an essential role in the ...
Blasco Moreno, Bernat (Date of defense: 2016-06-03)
The exonuclease Xrn1 degrades messenger RNAs (mRNAs) and controls transcription. By using a model system that replicates brome mosaic virus (BMV) in yeast, here we show that Xrn1 promotes translation ...
Mina Ibarra, Leonardo Bruno (Date of defense: 2010-05-21)
The group of positive strand RNA ((+)RNA) viruses includes numerous plant, animal and human pathogens such as the hepatitis C virus (HCV). Their viral genomes mimic cellular mRNAs, however, besides ...
Pérez Vilaró, Gemma (Date of defense: 2012-11-16)
Els cossos de processament (cossos-P) són grànuls discrets i dinàmics que contenen mRNAs represos en la traducció així com proteïnes involucrades en la degradació dels mRNAs i de la maquinària dels ...
Talló Parra, Marc (Date of defense: 2019-12-17)
La rellevància clínica dels virus transmesos per mosquits, com el virus del dengue (DENV), el virus del zika (ZIKV), el virus del chikungunya (CHIKV) i el virus del Nil Occidental (WNV), ha augmentat ...