Farré Ramon, Xavier (Date of defense: 2022-07-01)
Ageing is a very complex phenotype that has been widely studied, but is still largely unknown. Most of the studies focus on a single species, or on performing genome wide association studies in human ...
Sodaei, Reza (Date of defense: 2020-05-22)
How do genomes generate different tissues, behaviours, individuals or species? We try to identify parts of the human transcriptome that we found only in a tissue. Then, we focus on inter-individual ...
Platania, Leonardo (Date of defense: 2023-10-11)
The South Pacific is an intriguing region for studying evolutionary biology, presenting an exceptional diversity and complex geological and environmental characteristics. New Caledonia, in particular, ...
Balart i García, Pau (Date of defense: 2023-02-24)
Under very specific pressures, evolution turns extremely convergent, to the extent that distantly-related organisms show highly similar morphological, physiological and behavioral adaptations. Life into ...
Mantica, Federica (Date of defense: 2023-05-11)
Regulated Gene Expression (rGE) and Alternative Splicing (rAS) are two of the main mechanisms contributing to tissue-phenotypic diversity within and between species. In this thesis, we aim at characterizing ...
Pich Roselló, Oriol (Date of defense: 2021-03-24)
Cells of our body are constantly exposed to events that can create lesions in the DNA. If unremoved by the DNA repair mechanisms, the lesion may lead to a mutational event. Some of these events might ...
Torres Méndez, Antonio (Date of defense: 2020-02-28)
Post-transcriptional networks control multiple aspects of neuronal biology and their deregulation has been associated with human neurological disorders. This thesis focuses on regulation at the level ...
Bonforti, Adriano (Date of defense: 2022-07-27)
L'aparició de la pluricel·lularitat (MC) va definir un esdeveniment evolutiu important en la història de la vida al nostre planeta. Ha tingut lloc diverses vegades dins de grups independents i diferents ...
Heredia Genestar, José María (Date of defense: 2020-01-28)
La mutació és un procés essencial per l’evolució, tot i que també té un rol important tant en el càncer com en altres malalties. Les mutacions no s’acumulen uniformement al llarg del genoma i la seva ...
Renom, Pere (Date of defense: 2023-02-22)
According to estimates, over the 3.5 billion years that have elapsed since the appearance of life, the Earth has been inhabited by some 4 billion different species, of which 99.99% have already become ...