Timón Pérez, Krystal (Date of defense: 2018-12-18)
During mitosis, the microtubules organize a bipolar spindle that segregates the chromosomes. In higher eukaryotes, these microtubules are nucleated through three different pathways involving the centrosomes ...
Cavazza, Tommaso (Date of defense: 2015-10-30)
To ensure faithful segregation of the genetic material, during mitosis the cell assembles the mitotic spindle, a macromolecular machine made of dynamic microtubules and associated proteins. Spindle ...
Mòdol Cano, Aitor (Date of defense: 2021-04-29)
El cilio primario es una estructura formada por microtúbulos que sobresale de la superficie celular durante G0 teniendo una función de orgánulo sensor. La importancia del cilio es patente por las ...
Ferreira, Vanessa Miriam dos Reis (Date of defense: 2010-11-22)
Xkid is a Xenopus chromokinesin required for metaphase chromosome alignment and for meiosis I to meiosis II transition in oocytes. The aim of this work was to study the regulation of Xkid by phosphorylation ...
Laguillo Diego, Alejandra (Date of defense: 2021-03-12)
During cell division, microtubules (MTs) organize into a bipolar spindle that drives faithful chromosome segregation through the kinetochore fibers (k-fibers), bundles of parallel MTs that attach the ...
Lioutas, Antonio (Date of defense: 2012-11-09)
Aurora A (AurA) is an important mitotic kinase mainly studied for its involvement in cell cycle progression, centrosome maturation, mitotic spindle pole organization and bipolar spindle formation. ...
Rosas Salvans, Miquel (Date of defense: 2017-12-19)
Three microtubule (MT) assembly pathways participate in the assembly of the bipolar spindle: the centrosomal pathway, the augmin dependent amplification pathway and the RanGTP/chromosome dependent ...
Scrofani, Jacopo (Date of defense: 2014-10-10)
During mitosis, spindle assembly involves different sources of microtubules including centrosomes and chromosomes. While the role of centrosomes has been extensively studied, we still do not fully ...