Delli Ponti, Riccardo (Date of defense: 2019-01-16)
The secondary structure of an RNA molecule is fundamental for its function. However, structural conservation and the structure of RNA in vivo are still poorly understood. Data from recent high-throughput ...
Armaos, Alexandros (Date of defense: 2020-01-23)
Despite what was previously considered, the role of RNA is not only to carry the genetic information from DNA to proteins. Indeed, RNA has proven to be implicated in more complex cellular processes. ...
Doerr, Stefan (Date of defense: 2016-09-16)
Molecular dynamics has established itself over the last years as a strong tool for structure-based molecular investigation in biology. Stefan Doerr's thesis concerns the application of machine learning ...
Pérez Culubret, Adrià (Date of defense: 2022-01-27)
Caracteritzar la dinàmica de les proteïnes és essencial per tal d'entendre la connexió entre seqüència i funció. La simulació de dinàmiques moleculars és una de les tècniques principals per a estudiar ...
Morales Pastor, Adrián (Date of defense: 2024-04-11)
G protein-coupled receptors (GPCRs) are central to cellular signaling and pivotal in drug development. This thesis investigates allosteric communication in GPCRs, crucial for their effective modulation ...
Cabús, Lluc (Date of defense: 2024-03-15)
RNA is a molecule that is released by the different tissues into the circulation. When it is found in the circulation it is called cell-free RNA (cfRNA). This type of molecule has great potential as ...