Development of sol-gel silica-based 3D printable materials with tunable degradation, mechanical properties and drug release capacity for tissue engineering

Author

Rodríguez González, Raquel

Director

Pérez Antoñanzas, Román

Delgado Garoña, Luis María

Date of defense

2023-02-07

Pages

199 p.



Department/Institute

Universitat Internacional de Catalunya. Departament de Ciències Bàsiques

Abstract

The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body cannot regenerate large bone defects by itself. Nowadays, grafting is the main therapy, which is the replacement of missing bone with a graft. However, the use of grafts has some drawbacks, such as a limited availability, tissue rejection, donor site morbidity and infection. For this reason, Tissue Engineering has focused on the development of synthetic grafts in the form of scaffolds which are three dimensional porous structures that provide a 3D environment for the adhesion, proliferation, and differentiation of cells to produce new bone.

Keywords

Silica; Hybrids; Hybrids; 3D Printing; Bone regeneration; Sol-gel; Inks; Silica-gelatin; Tissue engineering; Gelatin

Subjects

61 - Medical sciences

Knowledge Area

Ciencias de la salud

Documents

This document contains embargoed files until 2025-02-06

Rights

L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/4.0/
L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/4.0/

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