Urdiroz Urricelqui, Uxue (Date of defense: 2022-04-07)
El papel que juega el metabolismo lipídico en la progresión del cáncer está siendo revisado. Estudios recientes de nuestro laboratorio demuestran que el tratamiento con ácido palmítico (AP) de ...
Zimmermann, Fabian (Date of defense: 2021-11-24)
The microtubule nucleator γ-tubulin ring complex (γTuRC) is essential for the function of microtubule organizing centers such as the centrosome. Since its discovery over two decades ago, γTuRC has evaded ...
López Cerro, Maria Teresa (Date of defense: 2018-06-29)
Chlamydomonas reinhardtii has emerged as a promising alternative host for recombinant protein expression. Despite its advantageous characteristics and low-cost production, its use is hampered by low ...
Ledda, Angelo (Date of defense: 2016-12-15)
La actividad antiinflamatoria de dosis farmacológicas de glucocorticoides (GCs) los ha convertido en una de las familias de fármacos más utilizados en las últimas décadas a pesar de que su prescripción ...
Oliva Lorenzo, Laia (Date of defense: 2019-06-27)
El sobrepeso y la obesidad son condiciones patológicas, con una prevalencia elevada, que están consideradas como una de las principales causas de mortalidad. Los factores genéticos, y especialmente, ...
Mateo Campins, Patricia (Date of defense: 2018-10-17)
La present tesi doctoral està enfocada al desenvolupament de noves petites molècules dirigides a diferents dianes del càncer. Els descobriments recents sobre la seqüenciació genòmica del càncer han ...
Antolin Fontes, Albert (Date of defense: 2019-03-07)
The mitochondrial Seryl-tRNA Synthetase (SerRS2) is a member of the class II tRNA synthetase family. The mature enzyme catalyses the ligation of serine to tRNASer in mitochondria. During the process of ...
Zuazo Gaztelu, Iratxe (Date of defense: 2018-11-23)
Tumor progression is a complex conundrum of events that involve not only tumor cells, but also their surrounding microenvironment. Accounting to the natural dependency of tumors on angiogenesis, its ...
Casas Masnou, Eduard (Date of defense: 2019-11-25)
Gene regulation mechanisms control the level of transcription of each gene into RNA and the combination of expressed genes determines cell identity. Gene regulation is maintained by epigenetic mechanisms ...
Martí Coma-Cros, Elisabet (Date of defense: 2019-09-27)
Malaria is an infectious disease that affects nearly half of the population in 90 countries around the world. In 2017 it was estimated that there were 219 million cases and 435,000 deaths disproportionately ...