Browsing by Title
Now showing items 18060-18079 of 41831
Exploring liver and adipose tissue alterations in the natural course of non-alcoholic fatty liver disease: A lipidomic Approach
L'obesitat és un problema de salut mundial on el 60-90% dels pacients desenvoluparan la malaltia del fetge gras per causa no alcohòlica (NAFLD), sent la principal manifestació hepàtica de la síndrome metabòlica. Tenint ...
Exploring metallosalen complexes in materials science and catalysis
Los complejos “metalosalen” [salen = N,N’-bis(salicilideno)etilendiamina] han sido objeto de estudio en la catálisis homogénea y últimamente también en la ciencia de materiales y catálisis multimetálica. En cuanto a esto, ...
Exploring Molecular Diversity: There is Plenty of Room at Markush's
L'estratègia de les etapes inicials del descobriment de fàrmacs està normalment basada en un procés anomenat hit-to-lead que implica un extens estudi entorn de la síntesi de derivats d'una molècula original que prèviament ...
Exploring molecular mechanisms of key targets in metabolic and infectious diseases
This doctoral thesis is focused on disclosing molecular factors that regulate the functional mechanism of key targets in i) metabolic disorders, such as diabetes and obesity, and ii) tuberculosis (TB). These diseases have ...
Exploring new approaches in urban water governance: case studies in mediterranean areas
Muchas de las ciudades costeras del mundo se están volviendo cada vez más urbana y muchas de ellas están cambiando hacia el turismo, uno de los sectores de mayor crecimiento de la economía mundial. El agua es un elemento ...
Exploring new gold-catalyzed cyclization reactions of 1,5-enynes and development of an intermolecular phenol synthesis
Las sales de oro se han convertido en uno de los catalizadores por excelencia en una gran variedad de transformaciones orgánicas mediante la activación selectiva de alquinos, alenos y alquenos. Parte del trabajo de esta ...
Exploring novel dye concepts in dye sensitized solar cells
Aquesta tesi es basa en un tipus de dispositius fotovoltaics, les cel•les solars sensitivitzades amb colorant. Des de fa un parell de dècades, l’estudi d’aquests dispositius ha anat en augment i actualment ja s’han publicat ...
Exploring protein structure changes due to somatic mutations in cancer
[eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient and improve their ...
Exploring quantum many-body systems from an entanglement and nonlocality perspective
Entanglement and non-local correlations give rise to unprecedented phenomena with no classical analogue. As a result, they have settled themselves as fundamental properties in the study of quantum many-body systems, as ...
Exploring quantum memory schemes in cold atoms for quantum repeaters
(English) Quantum memories are devices that are able to store photonic quantum states and entanglement. Future quantum networks, which could enhance cybersecurity through quantum key distribution, improve the precision in ...
Exploring Rubisco molecular evolution and kinetics temperature dependency
Rubisco, the enzyme that catalyzes the assimilation of atmospheric CO2 and sustains the vast majority of food chains in the Biosphere, presents functional inefficiencies limiting the photosynthetic process. Rubisco is ...
Exploring Signatures of New Physics in Cosmology
Cosmology is the study of the origin and evolution of our Universe as a whole. Even if the theoretical framework of Cosmology was developed a century ago, with the formulation of General Relativity by Albert Einstein, it ...
Exploring standardization and integration in the implementation of industry inter-organizational information systems: a case study in the seaport of Barcelona
Aquesta tesis presenta un estudi interpretativista sobre els processos d'estandardització i integració relacionats amb la implementació d'un sistema d'informació inter-organitzatiu (SIIO) sectorial en el Port de Barcelona. ...
Exploring structure-function relationship of the mitochondrial DNA packaging protein Abf2p and its dialogue with the DNA
Mitochondria are intracellular double-membrane bound organelles in eukaryotic cells that act as the major suppliers of adenosine triphosphate (ATP). They possess their own DNA (mtDNA) that codes for components of the ...
Exploring synthetic strategies for the production of complex inorganic nanoparticles
Los nanomateriales han sido un área intrigante de investigación científica en las últimas décadas, dada sus particulares propiedades físico-químicas que los hacen adecuados para aplicaciones en campos como fotonica, ...
Exploring T-DNA gene mechanisms and optimizing centelloside production in Centella asiatica hairy root cultures
[eng] Plant biofactories constitute an eco-friendly alternative to chemical synthesis as they have a lower environmental impact and therefore contribute to a more sustainable future. Hairy root cultures, generated by ...
Exploring the applications and limitations of location-based social network data in urban spatiotemporal analysis
Nowadays, the widespread utilization of intelligent mobile and located-embedded services extends the border of social network sites (SNS) to physical-spatial space. The appearance of SNS changes our daily life meanwhile ...
Exploring the butterfly speciation continuum : A study on butterfly speciation in the transition to genomic techniques
Butterflies are among the best studied animals, but despite the research efforts carried out during centuries, our knowledge on their diversity and on the mechanisms generating it is still incomplete. In order to understand ...
Exploring the diversity of geranylgeranyl diphosphate synthases in Arabidopsis thaliana and Solanum lycopersicum
Los isoprenoides forman la familia más amplia de metabolitos naturales y son especialmente diversos en el reino vegetal. Muchos isoprenoides vegetales con funciones esenciales y especializadas derivan del geranilgeranil ...
Exploring the Drug-Adverse Reaction and Drug-Target Landscape through Networks, Statistics and Machine Learning Approaches
The amount of attrition in drug discovery, particularly at advanced stages, is quite high due to unexpected adverse drug reactions (ADRs) generated by drug candidates; hence, being able to anticipate unexpected reactions ...
