Browsing by Title

Identificación, localización y función de las acuaporinas en el espermatozoide equino y su relación con la criopreservación

Bonilla Correal, Sebastian (Date of defense: 2019-10-04)

Esta tesis titulada “Identificación, localización y función de las acuaporinas en el espermatozoide equino y su relación con la criopreservación” está dividida en varias secciones. La primera parte contiene un sumario, ...

Identification and analysis of risk factors associated with Lost to follow up from tuberculosis treatment in Sanatorium Hospital in Luanda

Vita, Domingos (Date of defense: 2023-01-20)

La tuberculosi (TB) continua sent un greu problema de salut pública a causa de les altes taxes de prevalença, incidència i mortalitat que provoca anualment a les comunitats. L’objectiu de l’estudi és identificar i analitzar ...

Identification and characterisation of transcriptional regulators through proximity interaction mapping in two distinct systems

Lewis, Michael (Date of defense: 2022-11-11)

[eng] Transcriptional regulation is a multifaceted and fundamental process, which underpins normal physiology, and its dysregulation is associated to numerous pathologies. Using two inherently different transcriptional ...

Identification and characterization of a novel population of memory B cells in the human intestine

Comerma Blesa, Laura (Date of defense: 2016-07-12)

We found that IgM+IgD- memory (ME-M) B cells formed a large reservoir of intestinal antigen-selected IgM+ lymphocytes distinct from antigen-naïve IgM+ lymphocytes. Human ME-M B cells colonized the intestine early in life, ...

Identification and characterization of Adenosine A(2A) heteromers in the CNS = Identificació i caracterització d’heteròmers d’Adenosina A2A al SNC

Brugarolas Campillos, Marc (Date of defense: 2013-12-20)

The aims of this thesis are: Aim 1. The involvement of A(1)R-A(2A)R heteromer in glial cells and its study at a molecular level. Aim 2. To find evidence for allosteric interactions between partner receptors in the ...

Identification and characterization of an oncogenic form of IKKα in colorectal cancer

Margalef González, Pol (Date of defense: 2014-02-17)

L’IKKα nuclear regula la transcripció gènica i ha estat relacionada amb la progressió del càncer i la metàstasis, tot i que la connexió mecanística no s’entén massa bé. Hem observat que les ...

Identification and characterization of candidate genes for peach fruit shape

Zhang, Yu (Date of defense: 2018-11-28)

El fruit del préssec deriva de l'ovari madur, que es converteix en drupa. La seva forma pot variar entre rodona i plana, adquirint algunes formes intermèdies com la forma aplanada. En el préssec, el fruit pla (anomenat ...

Identification and characterization of cystinuria modulating genes: L-Ergothioneine as a potential treatment for preventing cystine lithiasis

Mayayo Vallverdú, Clara (Date of defense: 2021-11-29)

[eng] Cystinuria, with a worldwide prevalence estimated at 1:7000, is a rare inherited disease characterized by urine hyperexcretion of cystine and dibasic amino acids. Its clinical manifestation is cystine lithiasis in ...

Identification and characterization of disease-related copy number variations (CNVs) by high-dense SNP oligonucleotide microarrays

Rivera Brugués, Núria (Date of defense: 2012-03-20)

Genomic microarray analysis is rapidly replacing conventional chromosome analysis by molecular karyotyping due to the significant increase in the power to detect causative CNVs. Here, we extensively validated the HumanHap550 ...

Identification and characterization of microRNAs in porcine circovirus type 2 and African swine fever virus infections in vivo

Núñez Hernández, Fernando (Date of defense: 2016-09-30)

Cuatro estudios diferentes fueron llevados a cabo con el fin de analizar la expresión de microRNAs (miRNAs) porcinos y virales en dos infecciones in vivo diferentes con circovirus porcino tipo 2 (PCV2) y el virus de la ...

Identification and characterization of new complex patterns of structural DNA and RNA alterations in cancer

Delgado Serrano, Luisa Fernanda (Date of defense: 2021-12-02)

Human cancer arises as a result of genomic alterations that transform cells and make them to grow without control and to pathological levels. The characterization of such genomic changes has enabled understanding tumor ...

Identification and characterization of non-coding genomic variations associated to cancer diseases

González Rosado, Santiago (Date of defense: 2016-04-28)

The genetic and molecular bases of most of the human diseases have become one of the main goals of the human biology in the last decades. To be able to unveil the genetic variations and the affected cellular processes ...

Identification and characterization of novel latency-reversing agents to clear HIV-1 viral reservoir

García Vidal, Edurne (Date of defense: 2019-10-15)

La terapia antirretroviral ha cambiado la perspectiva sobre la infección por VIH-1 de enfermedad letal a crónica. Aun así, el reservorio latente del VIH-1 es una de las mayores barreras para lograr una cura. La estrategia ...

Identification and characterization of the molecular pathways regulating the cell cycle-linked pluripotency exit

Alcaine Colet, Anna (Date of defense: 2019-11-04)

The self-renewing nature of embryonic stem cells (ESCs) is a consequence of their ability to proliferate while maintaining pluripotency, by means the capacity to differentiate into all adult cell types. Despite the remarkable ...

Identification and characterization of the TRPVs protein-protein interactions, a comprehensive approach to elucidate TRPVs function and regulation

Doñate Macian, Pablo (Date of defense: 2016-07-13)

Los canales TRPV son canales de cationes que participan en la homeostasis del calcio con propiedades de activación polimodales. Los TRPVs regulan los niveles de calcio intracelular y promueven ...