Universitat de Barcelona
Ara mostrant els elements 10205-10224 de 11164
During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical molecules with high ...
Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by the combination of nasal polyps (NPs), chronic hypertrophic eosinophilic sinusitis, asthma and severity to any medication that inhibits ...
In our Galaxy, supernova remnants and pulsars are the two most numerous populations of non-thermal objects. The goal of this thesis is to study the extreme gamma-ray emission from these two astrophysical objects with Fermi ...
The calcineurin inhibitor Tacrolimus (Tac) is used to prevent acute rejection after renal transplant. Unfortunately, the clinical use of Tac is complicated by its considerable toxicity, narrow therapeutic window, and high ...
<b>THESIS SUMMARY:</b><br/><br/>The possibility to print tiny amounts of functional materials in a controllable way is of interest in a large number of applications, for instance in the manufacturing of organic electronics, ...
Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better comprehension of the process ...
The oncogenic properties of E2F1 have been traditionally associated with the role of the oncogene in proliferation, but during the last few years many other functions associated with this family of transcription factors ...
Huntington's disease (HD) and Parkinson's disease (PD) are devastating neurodegenerative diseases that progress with the death of selective neuronal subpopulations. Neuronal dysfunction and death are consequence of multiple ...
Nek9 is a NIMA-related kinase that is phosphorylated in mitosis and a small pool of it (5%) is activated at the centrosomes by a complex mechanism which has remained elusive until now. Nek6 and Nek7 bind to the C-terminal ...
Carnitine palmitoyl transferase 1 (CPT1) enzymes catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, thus facilitating the entry of long-chain fatty acids to the mitochondria, where they undergo β-oxidation. ...
Venous Thrombosis (VT) is a frequent complex disease that involves a disruption of the balance of the hemostatic system. microRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Promising findings in ...
[eng] The application of mechanical force to the nucleus has been recently shown to regulate important functions, including nucleocytoplasmic transport (NCT), chromatin organization, and gene expression. However, how ...
Body axis elongation is a hallmark of the vertebrate embryo, which also comprises the morphogenesis of the caudal neural tube (NT). The contribution of bipotential neuromesodermal progenitors (NMPs) to the cranio-caudal ...
The radiative transfer cannot be explicitly resolved in the atmospheric models for two reasons: i) a full treatment of the radiative transfer equation (RTE) requires a high amount of computational resources and ii) the ...
Due to the current interest on intermetallic compounds (IMCs), specially for their use at high temperatures being capable to substitute superalloys and, for the lately improvement of their lack of ductility, this work ...
Nowadays there is a growing interest in the capture and utilization of CO2 because of the increase of its concentration in the atmosphere. Captured CO2 can be recycled through different processes to obtain several value-added ...
During the last century, cellular biology has been mostly assessed from the biochemical point of view: studying how biochemical stimuli modify the biochemical composition of living cells. However, most of the cells that ...
The aim of this 4 year long work was to study the Connexin32 (Cx32), a protein that forms hemichannels anchored in the plasma membrane. Two hemichannels of adjacent cells form a gap junction. Mutations in Cx32 have been ...
In the first years of life, there is a dramatic unfolding of cognitive abilities supported by the progressive control of gaze behaviour. The early development of oculomotor control is presumably closely tied to the maturation ...
The objective of my thesis was to develop novel techniques and methods to probe the dielectric properties of biomembranes in air and their natural environment - liquid solution. The dielectric constant ε(r) of biomembranes ...
