Ara mostrant els elements 4891-4910 de 11175

    Exploiting circulating lymphocytes and cell-free DNA as a source to develop minimally-invasive personalized T-cell therapies 

    Garcia Garijo, Andrea (Data de defensa: 2023-05-26)

    [eng] Adoptive cell transfer (ACT) of tumor-infiltrating lymphocytes (TILs) can medi- ate tumor regression in patients with metastatic melanoma. Retrospective studies of TIL products from responders and non-responders have ...

    Exploració computacional de compostos bioactius: reactivitat i interacció lligand-receptor 

    Llabrés Prat, Salomé (Data de defensa: 2015-07-09)

    La present tesis doctoral, presentada com a compendi de publicacions, té com a objectiu general l’estudi de la diversitat en l’espai químic i l’establiment de relacions amb l’espai biològic mitjançant l’ús de tècniques ...

    Exploración de aguas subterráneas en el Arco Seco de Panamá (Sector de Las Tablas) mediante métodos geofísicos 

    Caballero, Alberto (Data de defensa: 2010-01-19)

    La investigación se ha desarrollado en la región de Las Tablas, ubicada en el denominado Arco Seco de la República de Panamá. En esta región, el abastecimiento de agua potable, debido al aumento de la población, se ve ...

    Exploración de la comunicación estratégica digital, Redes Sociales de equipamientos patrimonio mundial en Barcelona. El caso de: Casa Batlló, Casa Milà - La Pedrera y Casa Vicens 

    Salazar Morales, Lizeth (Data de defensa: 2021-12-21)

    La aparición en la última década de Redes Sociales digitales y de su papel indispensable como plataformas de comunicación en el contexto global de las organizaciones, así como la transformación de públicos, espectadores ...

    Exploración de las prácticas de lectura digital académica en estudiantes de un grado de Educación: Investigación con métodos mixtos 

    Abarzúa Ceballos, Leonel (Data de defensa: 2023-12-18)

    [spa] La presente tesis aborda la lectura digital como una práctica social situada en un contexto de formación universitaria. Su fundamentación teórica proviene de los ámbitos de la lectura digital, la teoría de la práctica ...

    Exploración de los conocimientos, actitudes y creencias de los docentes para la integración de las tecnologías en el aula 

    Paidicán Soto, Miguel Ángel (Data de defensa: 2023-09-12)

    [spa] Los constantes avances de las tecnologías digitales han traído, como consecuencias, la necesidad de mejorar los conocimientos y habilidades de los docentes, en áreas relacionadas con lo disciplinar, pedagógico y ...

    Exploración y modelización de patrones socioecológicos y tecnoculturales en sociedades preindustriales de zonas áridas afro-eurasiáticas. Una aproximación multidisciplinar desde métodos cuantitativos 

    Angourakis, Andreas (Data de defensa: 2018-11-19)

    Esta tesis doctoral trata la exploración y modelización formal de patrones socioecológicos y tecnoculturales, así como de algunos de los hipotéticos mecanismos que los explicarían. Los patrones se postulan sobre dos tipos ...

    Exploration of Extracellular Vesicles as a Novel Approach for Antigen Discovery and Vaccine Development against Plasmodium vivax Malaria 

    Díaz Varela, Míriam (Data de defensa: 2019-11-28)

    Plasmodium vivax is the most geographically widespread human malaria parasite. Research on this parasite needs to be expanded in order to develop adequate tools for its control such as a highly effective vaccine. One ...

    Exploration of sulfated polysaccharides as antimalarials and as targeting molecules for nanovector-mediated drug delivery to Plasmodium-infected cells 

    Marques, Joana (Data de defensa: 2015-12-14)

    Malaria is arguably one of the main medical concerns worldwide because of the numbers of people affected, the severity of the disease and the complexity of the life cycle of its causative agent, the protist Plasmodium spp. ...

    Exploring adamantine-like scaffolds for a wide range of therapeutic targets 

    Valverde Murillo, Elena (Data de defensa: 2015-10-30)

    For over eighty years, adamantane ring has interested organic chemists for its simplicity and symmetry. The rigid tricyclo[3.3.1.13,7]decane skeleton has provided a unique structural template for evaluating important ...

    Exploring autobiographical memories: from neurocognitive mechanisms to real-life experience 

    Nicolás Berenguer, Berta (Data de defensa: 2020-10-28)

    Our daily life event experiences fall into two general classifications: those that are remembered and those that are not. The act of remembering involves a perfect gearing of neurocognitive operations that begin with the ...

    Exploring Food System Transformations in Spain (1980-2021) 

    Parajuá Carpintero, Noelia (Data de defensa: 2023-12-20)

    [eng] In this PhD Thesis, I examine the transformations of the Spanish food system from 1980 to the present, focusing on its socioeconomic structural changes and their impacts on sustainability and social equity. My research ...

    Exploring heterocyclic scaffolds in the development of multi-target anti-Alzheimer and multi-trypanosomatid compounds 

    Di Pietro, Ornella (Data de defensa: 2015-11-06)

    The aim of this PhD thesis consists of the synergistic combination of both highly efficient synthetic approaches and molecular modelling tools for the structure-based drug design and synthesis of novel bioactive heterocyclic ...

    Exploring lifelong learning motivational ecologies through the narratives of senior language users 

    Darnault, Bérénice (Data de defensa: 2023-07-11)

    [eng] In the context of an ageing and increasingly more independent learning population, a narrative inquiry into the life stories of highly motivated senior language users remains a promising yet relatively unexplored ...

    Exploring molecular mechanisms of key targets in metabolic and infectious diseases 

    Aledavood, Elnaz (Data de defensa: 2021-10-01)

    This doctoral thesis is focused on disclosing molecular factors that regulate the functional mechanism of key targets in i) metabolic disorders, such as diabetes and obesity, and ii) tuberculosis (TB). These diseases have ...

    Exploring protein structure changes due to somatic mutations in cancer 

    Diéguez Docampo, Andrea (Data de defensa: 2023-03-02)

    [eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient and improve their ...

    Exploring Signatures of New Physics in Cosmology 

    Bellomo, Nicola (Data de defensa: 2020-01-24)

    Cosmology is the study of the origin and evolution of our Universe as a whole. Even if the theoretical framework of Cosmology was developed a century ago, with the formulation of General Relativity by Albert Einstein, it ...

    Exploring structure-function relationship of the mitochondrial DNA packaging protein Abf2p and its dialogue with the DNA 

    Chakraborty, Arka (Data de defensa: 2016-07-08)

    Mitochondria are intracellular double-membrane bound organelles in eukaryotic cells that act as the major suppliers of adenosine triphosphate (ATP). They possess their own DNA (mtDNA) that codes for components of the ...

    Exploring T-DNA gene mechanisms and optimizing centelloside production in Centella asiatica hairy root cultures 

    Alcalde Alvites, Miguel Angel (Data de defensa: 2023-12-19)

    [eng] Plant biofactories constitute an eco-friendly alternative to chemical synthesis as they have a lower environmental impact and therefore contribute to a more sustainable future. Hairy root cultures, generated by ...

    Exploring the heavy atom effect and supramolecular assemblies of Au(I) and Pt(II) complexes 

    Romo Islas, Guillermo (Data de defensa: 2023-07-14)

    [eng] This thesis is mainly focused on studying the photophysical properties of Au(I), Ag(I), Cu(I), and Pt(II) coordinated compounds. This work can be divided into two parts: on the one hand, the compounds of the group ...