Universitat de Barcelona
Now showing items 7946-7965 of 11039
The pleiotropic WT1 transcription factor (WT1) was first discovered in renal tumours. It contains four zinc-finger motifs at the C-terminus which are important for DNA binding to activate gene expression and is also involved ...
Lycopene is an antioxidant carotenoid present in high amounts inside the ripe tomato fruit, in watermelon, red bell pepper and a few other red-pigmented fruits. Its health benefits, notably the prevention of prostate cancer ...
Maldacena's conjecture, often known as the holographic duality or the AdS/CFT correspondence, proposes an equivalence between gravitational theories in a hyperbolic space of a certain dimensionality and gauge theories ...
[eng] Speaking metaphorically, the human nervous system is a complex ensemble of millions of parts operating together one with another. For this reason, each part is fundamental for the correct function of the whole system. ...
The aim of the present thesis is directed towards the comprehension of the mechanisms involved in the regulation of lipid and carbohydrate metabolism in relevant species in European aquaculture. Special attention has been ...
Receptor activator of nuclear factor kappa-β ligand (RANKL) and its receptor RANK are key mediators of bone resorption1,2. RANKL, its receptor RANK and its natural decoy receptor OPG, which is a competitive inhibitor that ...
Sphingolipids (SLs), essential components of cell membranes, are bioactive molecules involved in the regulation of a variety of cellular processes. Ceramide and sphingosine generally mediate anti-proliferative stimuli, ...
[eng] The present dissertation aims at broadening current knowledge regarding the importance of bodily or tissue status of bioactive compounds that are highly abundant in the Mediterranean diet (carotenoids and polyphenols) ...
Colorectal cancer (CRC) is one of the most frequent malignancies worldwide and it is considered an important healthcare problem. Moreover, colorectal carcinogenesis is a long stepwise process through a known precursor, the ...
Transforming growth factor-beta (TGF-β) is an important growth suppressor in hepatocytes, inhibiting proliferation and inducing cell death. However, it also plays a role in other processes such as epithelial-to-mesenchymal ...
Marine ecosystems are directly threatened by multiple and interactive human stressors at global and local scales. Hence, it is vital to study biodiversity and ecological patterns through a multi-disciplinary approach, from ...
Mercury (Hg) is naturally present in the Earth’s crust, however the historical use of this metal by the human being has spread and increased its presence in the environment. Both inorganic and organic species can be found ...
[eng] This thesis explores British Vogue’s self-appointed role as a guide to modern fashions and manners, that is, as a cultural intermediary, during the interwar period (1918-1939). Through a close reading of its essays, ...
Malaria is responsible of almost half a million deaths every year. Currently, campaigns for the control and elimination of malaria are implemented in malaria endemic areas. However, drug resistance is one of the major ...
In this thesis we have studied the influence of transport mechanisms on the adsorption kinetics of colloidal suspensions, as well as in the distribution of colloidal particles at the adsorbed layer. Adsorption of colloidal ...
The cell cycle, the group of processes involved in the duplication and division of a cell in two daughter cells is essential for all organism existence. The correct regulation of these processes is crucial to guarantee ...
[eng] Introduction Congenital heart defects are the most common severe congenital malformations. Since prenatal diagnosis is optimal, current research focuses on studying cardiovascular remodeling to improve prognostic ...
The assessment of oxygen uptake (Vo2) in swimming is a complex and cumbersome procedure and still faces limitations imposed by the environment and the equipment. There are two different approaches to measure Vo2 in water: ...
The aim of this thesis is two-fold. First it provides a general methodology for applying image deconvolution to wide-field CCD imagery. Second, two new CCD observational techniques and two data analysis tools are proposed ...
[eng] The increasing demand on next-generation displays encourages an exhaustive research on the development of new and enhanced semiconductors. Apart from the conventional inorganic materials, organic-based semiconductors ...
