Aminocyclitol and iminosugar derivatives related to Gauche disease 

Monlleó Mas, Ester (Date of defense: 2016-11-25)

Gaucher disease (GD) is one of the most prevalent lysosomal storage diseases.A mutation on gene gba1 generates a misfolded enzyme acid β-glucosidase. Due to this, this enzyme is not properly transported from the endoplasmic ...