Cánovas Bilbao, Begoña (Date of defense: 2017-07-20)
In normal epithelial cells, p38α has a well-established role as a tumor suppressor. However, recent reports have illustrated pro-tumorigenic functions for the p38α pathway by promoting tumor cell survival ...
Román González, Lidia (Date of defense: 2014-01-31)
Within the hematopoietic system, all mature blood cells are generated. Every differentiation step is characterized by the activation of a new, lineage specific, genetic program and the extinction of the ...
Holtschlag, Claudia (Date of defense: 2014-04-24)
In this dissertation, I contribute to the literature that addresses why some people are more successful in their careers than others. Within this stream of research, scholars have increasingly examined ...
Oriolo, Giovanni (Date of defense: 2019-09-12)
INTRODUCTION. Sickness behavior is a highly organized adaptive strategy elicited by inflammation to support the organism’s defense against pathogens. It is characterized by changes in behavior, mood and ...
Marrone, Giusi (Date of defense: 2014-06-27)
Increased intrahepatic vascular resistance (IHVR), mainly due to elevated vascular tone together with the maturation of hepatic fibrosis and the drop of the hepatic endothelial function, is the main ...
Rey Jurado, Emma (Date of defense: 2013-02-11)
Tuberculosis (TB) remains a global threat worldwide with nearly nine million incident cases of TB. The emergence of M. tuberculosis resistance to antituberculous drugs has led to the need for careful ...
Petrillo, Giovanna (Date of defense: 2017-06-28)
The rapid progress in structural and molecular biology over the past fifteen years has allowed chemists to access the structures of enzymes, of their complexes and of engineered variants. This wealth ...
Garrido Martínez, María (Date of defense: 2012-12-14)
To study biological systems through the specific labeling of biomolecules by chemical reactions has grown interest in the last few years. In order to perform chemical reactions in living systems, it is ...
Bioque Alcázar, Miquel (Date of defense: 2013-10-14)
Around 3% of the general population suffers a first episode of psychosis (FEP). The population of FEPs represents a unique opportunity to study psychotic disorders in general and schizophrenia in ...
Márquez Arrico, Julia E. (Date of defense: 2017-07-18)
Dual Diagnosis (DD) refers to the co-existence of a Severe Mental Illness (SMI) and a Substance Use Disorder (SUD) in the same individual. The comorbid prevalence of these two diagnoses is very common, ...