Badiola Mateos, Maider (Date of defense: 2021-03-10)
Movement of skeletal-muscle fibres is generated by the locomotion circuit, in which many cells play a different role. Failures in any part of the circuit can cause or define the severity of neuromuscular ...
Baptista, Inês do Carmo Viegas (Date of defense: 2022-04-07)
Leukaemia is one of the types of cancer where treatment resistance is prevalent. Better understanding of leukemic cells metabolism opens possibilities for new therapeutic strategies and better prognosis ...
Moyà Anderico, Laura (Date of defense: 2021-04-26)
Galleria mellonella (greater wax moth) is a popular animal model that has been extensively used as an alternative in vivo model for investigating the virulence and pathogenicity of different bacteria. ...
Diaz Garrido, Natalia (Date of defense: 2021-11-17)
The gut microbiota establishes dynamic and complex interactions with the intestinal epithelium and the immune system. In this regard, commensal microbiota plays essential role in the development and ...
Català Moll, Francisco (Date of defense: 2020-06-08)
Epigenetic factors, such as histone post-translational modifications and DNA methylation, are critical determinants of gene expression, which ultimately defines cell identity and function. Despite intense ...
Rodríguez Escribà, Marta (Date of defense: 2020-01-21)
Transfer RNAs (tRNAs) are key adaptor molecules that mediate decoding of messenger RNAs (mRNAs) into proteins by complementary pairing of their anticodons with mRNA codons. tRNAs that undergo adenosine ...
Jiménez Panizo, Alba (Date of defense: 2021-12-14)
El receptor de glucocorticoides (GR) es un factor de transcripción que se expresa de forma ubicua y controla procesos esenciales para la vida como el metabolismo, la inflamación y la homeostasis. Aunque ...
Letelier Torres, Nicole Alejandra (Date of defense: 2021-12-14)
Obesity is nowadays considered a pandemic disease, and its incidence correlates with the concomitant increase of a set of associated comorbidities, including T2D, cardiovascular diseases, fatty liver ...
Rodríguez Lumbreras, Luis Ángel (Date of defense: 2023-04-18)
[eng] The study of the 3D structural details of protein-protein and protein-DNA interactions is essential to understand biomolecular functions at the molecular level. Given the difficulty of the structural ...
Barranco Muñoz, Neus (Date of defense: 2020-06-22)
The regulated secretory pathway is a hallmark of professional secretory cells as neurons and endocrine cells. Significant peptidergic neurotransmitters as hormones, neurotrophins and growth factors ...