Álvarez Marimón, Mª Elena (Date of defense: 2014-10-27)
Heteromeric amino acid transporters (HATs) mediate the transport of amino acids through the plasma membrane. They are composed of two subunits (a heavy and a light one) linked by a conserved disulfide ...
Cano Crespo, Sara (Date of defense: 2019-06-26)
The wide variety of disorders associated with the malfunction of amino acid (AA) transporters reflect the relevant roles they fulfil in human physiology. Heteromeric AA transporters (HATs), one of the ...
Escudero Bravo, Paloma (Date of defense: 2021-07-15)
Los transportadores heteroméricos de aminoácidos (HAT) se encuentran compuestos por una subunidad pesada que dirige el tráfico del transportador a la membrana plasmática y la subunidad ligera que posee ...
Sotillo Rodríguez, Fernando (Date of defense: 2018-02-16)
Lysinuric Protein Intolerance (LPI, MIM #222700) is a rare autosomic disease caused by mutations in SLC7A7 gene. Hallmarks of LPI are malabsorption and deficient renal reabsorption of cationic amino ...