Petazzi, Paolo (Date of defense: 2015-02-20)
INTRODUCTION To answer many complex and fascinating biological phenomena, we must go over or above (epi-) genetics because the DNA blueprint is identical in each of the abovementioned somatic cells. ...
Cherubini, Marta (Date of defense: 2016-01-15)
Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder, characterized by progressive behavioral, motor and cognitive deficits (HDCRG, 1993; Ross & Margolis, 2001). The ...
Via Virgili, Esther (Date of defense: 2015-11-25)
Anorexia nervosa (AN) is a severe disorder, accepted to be of a multifactorial etiology. Although there is evidence for alterations in neural networks contributing to the onset, development and maintenance ...
Uribe Codesal, Carme (Date of defense: 2019-05-03)
BACKGROUND AND OBJECTIVES. Parkinson’s disease is a heterogenous neurodegenerative disorder. To characterize homogeneous groups of PD patients, PD phenotypes have been described based on clinical data ...
Torao-Angosto, Melody (Date of defense: 2020-09-22)
The brain varies its state in accordance with the internal and external context, resulting into distinct patterns of activity and dynamics. The cerebral cortex and the interactions between cortical and ...
Biayna Rodríguez, Josep (Date of defense: 2016-01-22)
The role of neurofibromin, the product of the Neurofibromatosis Type 1 (NF1) gene, in cell physiology is still not well understood. Considering the different traits associated to NF1 it is clear that ...
Barbosa, João Moura (Date of defense: 2019-05-24)
Our ability to memorize is at the core of our cognitive abilities. How could we effectively make decisions without considering memories of previous experiences? Broadly, our memories can be divided in ...
Andrés Benito, Pol (Date of defense: 2019-12-17)
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are clinically distinct neurodegenerative diseases that are connected by genetic and pathological overlap. ALS patients ...
Yefimenko Nosova, Natalia (Date of defense: 2016-06-17)
AMPA receptors (AMPARs) are responsible for the 90% of synaptic transmission and are involved in plasticity, developmental and neurological processes. Their function depends on the proteins interacting ...
Monté Rubio, Gemma C. (Date of defense: 2015-12-17)
Chronic schizophrenia has been widely studied, consistent findings have shown the anatomical pattern associated with this disease, but the clinical picture is often undifferentiated at first presentation. ...