Nicolini, Federica (Date of defense: 2022-12-02)
[eng] Protein-protein interactions (PPIs) play a crucial role in the homeostasis of the cells; therefore, they are important therapeutic targets. Typically, the goal in targeting PPIs is to impede them. ...
Garcia Cabau, Carla (Date of defense: 2022-05-31)
Intrinsically disordered (ID) proteins or regions are protein sequences that lack stable secondary and tertiary structures. ID proteins are particularly prone to undergo liquid- liquid phase separation ...
Dávila Bouziguet, Eva (Date of defense: 2022-06-03)
The neuropathological hallmarks of Alzheimer’s disease are senile plaques, extracellular deposits of amyloid-β peptide (Aβ), and neurofibrillary tangles, intracellular aggregates of hyperphosphorylated ...
Solé Solé, Judith (Date of defense: 2022-06-03)
Following the laws of evolution, bacteria are capable of slowly but inexorably acquiring resistance to antibiotic compounds that we have been using for decades. Therefore, bacteria that seemed harmless ...
Hervés Carrete, Carmen (Date of defense: 2023-05-24)
[eng] The main objective of this dissertation has been to stablish a bridge between materials science and its fields of application. The scope of this thesis work, under this premise, is aimed towards ...
Ospina Álvarez, Natalia (Date of defense: 2012-06-27)
This doctoral thesis deals with the biogeochemical processes taking place in estuarine systems known as 'rias', located at the NW of the Iberian Peninsula. Its realization has been possible thanks to ...
Short, Kathleen (Date of defense: 2022-12-12)
[eng] The overwhelming evidence for the existence of dark matter in the Universe, and the discovery of the neutrino masses, are striking indicators of the need for new physics beyond the ΛCDM and Standard ...
León Moreno, Theresa Elizabeth (Date of defense: 2013-10-30)
Nuclear receptor LXR is a ligand dependent transcription factor. The activating ligands of LXR are specific oxidized forms of cholesterol (oxysterols) and intermediate products of the cholesterol ...
Taboada Moreno, Sergio (Date of defense: 2012-07-20)
Esta tesis cubre diferentes aspectos de los invertebrados marinos bentónicos de la Antártida. Se trata de una tesis multidisciplinar presentada en formato artículos en la que se hacen las siguientes ...
Climent Biescas, Claudia (Date of defense: 2017-07-07)
In this thesis, different organic and organometallic molecules with interest for optoelectronic applications have been studied from a computational standpoint. The work presented in this thesis belongs ...