Solé Sánchez, Sònia (Date of defense: 2015-11-17)
La via de Calcineurina (Cn)- Factor Nuclear de Cèl·lules T Activades (NFAT) ha estat descrita clàssicament com a via de senyalització essencial en el funcionament de les cèl·lules T del sistema immunològic ...
Tell Martí, Gemma (Date of defense: 2018-05-07)
El gen MC1R (codi OMIM: #155555) codifica pel receptor de la melanocortina 1 (MC1R) que s’expressa majoritàriament a la membrana dels melanòcits i està implicat en la regulació de la síntesi de melanina. ...
Izquierdo Cadenas, Vanesa (Date of defense: 2021-07-21)
Factores ambientales como el ejercicio, el estrés o la dieta contribuyen a la patogénesis de enfermedades asociadas al deterioro cognitivo y al envejecimiento, modulando mecanismos de expresión génica ...
Mazuelas Gallego, Helena (Date of defense: 2021-01-28)
Neurofibromatosis type 1 (NF1) is a genetic disease caused by inherited mutations in the NF1 gene. NF1 is a cancer predisposition syndrome, and the disease’s hallmark is the appearance of tumors of the ...
Díaz Gay, Marcos (Date of defense: 2019-11-25)
Colorectal cancer (CRC) is one of the malignant neoplasms with higher incidence and mortality in Spain, Europe and worldwide. As a complex disease, both environmental and genetic factors influence CRC ...
Sanchez Delgado, Marta (Date of defense: 2018-05-31)
Genomic imprinting is an epigenetic phenomenon resulting in the monoallelic expression of a subset of genes in a parent-of-origin-specific manner. In general, the promoters of these transcripts contain ...
Schikora Tamarit, Miquel Àngel (Date of defense: 2023-11-03)
[eng] Fungal infections pose a serious health threat, affecting >1,000 million people and causing ~1.5 million deaths each year. The problem is growing due to insufficient diagnostic and therapeutic ...
Meler Marquina, Ainara (Date of defense: 2023-06-29)
[eng] Proper B cell identity demands a tight controlled genomic and epigenomic landscape at each stage of cellular differentiation during B lymphocyte development. It has been previously identified in ...
Seuma Areñas, Mireia (Date of defense: 2023-01-18)
[eng] Proteins can adopt multiple conformations and material states, from soluble states to self- assemblies, such as liquid condensates or amyloids. Protein aggregation has been associated with many ...
Díez Obrero, Virginia (Date of defense: 2021-11-19)
[spa] La expresión genética es un proceso celular clave, que además está relacionado con la susceptibilidad genética a enfermedades y rasgos complejos. La mayoría de genes se someten a splicing alternativo ...