Jiménez Panizo, Alba (Date of defense: 2021-12-14)
El receptor de glucocorticoides (GR) es un factor de transcripción que se expresa de forma ubicua y controla procesos esenciales para la vida como el metabolismo, la inflamación y la homeostasis. Aunque ...
Giménez Carabaza, Neus (Date of defense: 2019-11-15)
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the western countries. It is currently an incurable disease. CLL is a B-lymphoid neoplasm in which the microenvironment plays a key role ...
Montal Roura, Robert (Date of defense: 2020-10-07)
[spa] El cáncer hepatobiliar (incluye principalmente el carcinoma hepatocelular [HCC] y el cáncer del tracto biliar [BTC]) representa la tercera causa de muerte relacionada con cáncer en todo el mundo ...
Ciscar García, Marina (Date of defense: 2022-10-03)
[spa] Durante el proyecto de tesis se han realizado dos proyectos: Por un lado, se ha investigado la biología de la vía de señalización de RANK en adenocarcinomas de mama humanos. Además, se han ...
Almici, Enrico (Date of defense: 2022-10-10)
[eng] The composition and architecture of the extracellular matrix (ECM), and their dynamic alterations, play an essential regulatory role in numerous cellular processes. Furthermore, structural, and ...
Morales Paytuví, Frederic (Date of defense: 2022-02-04)
The following sections of the thesis are divided in two parts corresponding with the two projects conducted, whose objectives are stated below. 1. Caveolin in the endoplasmic reticulum During ...
Feu i Coll, Sònia (Date of defense: 2019-03-28)
This thesis investigates the mechanisms that are activated in response to replication stress induced with hydroxyurea, an agent that causes deoxyribonucleotides depletion and arrest cells in S phase, ...
Requena Osete, Jordi (Date of defense: 2017-09-08)
Induced pluripotent stem cells (iPSC) can be made from adult somatic cells by reprogramming them with Oct4, Sox2, Klf4 and c-Myc. IPSC have given rise to a new technology to study and treat human disease ...
López del Hoyo, Natalia (Date of defense: 2014-03-14)
In the last two decades, it has been done a thoroughly research about the role of Guanylate Cyclase Activating Proteins (GCAPs) in photoreceptor cells of the retina as activity regulators of Retinal ...
Escribá Piera, Rubén (Date of defense: 2022-03-17)
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and a frequent cause of heart failure and sudden cardiac death. HCM is a highly complex condition defined by clinical and ...