Vendrell i Soler, Elisenda (Date of defense: 2005-04-07)
El càncer colorectal és una malaltia genètica que afecta principalment als països desenvolupats. A les fases inicials del desenvolupament del tumor es formen adenomes benignes, que amb el temps poden ...
Porta Pardo, Eduard (Date of defense: 2013-03-05)
In the era of “omics” data, the use of computational approaches to store, integrate and analyze biological information is becoming a priority, particularly in the field of biomedicine and the study of ...
Rodríguez Vaello, Victoria Eugenia (Date of defense: 2020-12-11)
A fundamental step in embryo development is the transition through pluripotency. There are two known sequential states of pluripotency termed naïve and primed pluripotency. Considerable efforts have ...
Bustamante Pineda, Mariona (Date of defense: 2007-09-18)
L'osteoporosi, una malaltia complexa determinada tant per factors genètics com ambientals, està caracteritzada per una reduïda densitat mineral òssia (DMO), un deteriorament de la microarquitectura òssia ...
Norris, Richard (Date of defense: 2021-10-13)
Insulinomas are extremely rare pancreatic neuroendocrine (PNET) tumours that develop from the β-cells of the pancreas.β-cells are the only cells capable of producing the hormine insulin, and play a major ...
Sebé Pedrós, Arnau (Date of defense: 2013-06-07)
The origin of animal multicellularity is a major evolutionary transition and a poorly understood one. In recent years, the sequencing of the genomes of several earlybranching metazoans, such as sponges ...
Lafzi, Atefeh (Date of defense: 2020-05-29)
Single-cell RNA sequencing has revolutionized the way molecular mechanisms were being studied by allowing the dissection of gene expression at single-cell resolution. The data acquired from scRNA-seq ...
Escuer Pifarré, Paula (Date of defense: 2022-12-21)
[eng] During the last decade, advances in high-throughput sequencing (HTS) technologies have increased exponentially the generation of genomic data, especially of non-model species. In this thesis, we ...
Fernández Vidal, Leyden (Date of defense: 2015-01-22)
Se ha demostrado en un número de estudios de metagenómica que la adición y la pérdida de genes específicos ha permitido a los microbiomas adaptarse a condiciones ambientales típicas de los entornos. ...
Igea de Castro, Javier (Date of defense: 2013-01-18)
Las filogenias que incorporan información procedente de distintos loci del genoma son fundamentales para resolver las relaciones evolutivas de los seres vivos, así como para determinar con precisión los ...