Moreta Moraleda, Cristina (Date of defense: 2022-01-25)
The hypothesis of the present thesis is that the presence or absence of some chromatin factors may facilitate or impair the action of chemotherapeutic drugs in colorectal cancer (CRC). Chromatin factors ...
Montero Martín, Sara (Date of defense: 2021-11-22)
Despite the latest advances in early diagnosis and increased resources employed to develop new therapeutic options, effective control of cancer disease remains a challenge. In fact, cancer is the second ...
Badia Ramentol, Jordi (Date of defense: 2020-01-14)
Colorectal cancer (CRC) is the second-highest cause for cancer-related mortality worldwide. Patients suffering from CRC generally don’t die from primary tumours but rather from metastasis, for which ...
Martín Liberal, Juan Jesús (Date of defense: 2016-11-07)
Sarcomas are a group of malignancies characterized by their bad prognosis and the absence of effective treatments. Median survival of advanced sarcoma patients is only one year in spite of treatment. ...
Nadal Sanmartin, Cristina (Date of defense: 2007-07-24)
1 INTRODUCCIÓN<br/><br/>El cáncer colorrectal (CCR) es la tercera causa de diagnóstico de cáncer en todo el mundo. El 11-27% de pacientes se diagnostican en estadio avanzado o metastático. De los ...
Albert Colomer, Nerea (Date of defense: 2021-01-18)
Tumor-stroma crosstalk is essential for PDAC formation. Therefore, the stroma, and specifically the carcinoma-associated fibroblasts (CAFs), are the target of therapeutic alternatives to treat highly ...
Aragó Belenguer, Marc (Date of defense: 2022-06-30)
[spa] La reprogramación metabólica es uno de los procesos que caracterizan el cancer. Estos cambios en el metabolismo de las células tumorales no solo permiten a las células obtener los metabolitos ...
Prieto Durán, Iván (Date of defense: 2022-09-16)
[spa] A día de hoy, el cáncer es la segunda causa de mortalidad en el ser humano y la mayoría de las muertes son producidas por la metástasis. Aunque se han postulado varias hipótesis para explicar ...
Cañellas Socias, Adrià (Date of defense: 2022-07-22)
Colorectal cancer (CRC) kills around 700,000 people worldwide every year. The majority of these deaths are the result of dissemination of the disease to foreign organs. Despite undergoing curative ...
Font Díaz, Joan (Date of defense: 2022-07-22)
Nuclear receptors are a superfamily of ligand-dependent transcription factors that are involved in numerous biological processes in homeostasis and disease. Liver X receptors (LXRs) are members of the ...