Pell Vidal, Núria (Date of defense: 2020-11-19)
Obesity is reaching pandemic dimensions and is an established instigator of many diseases, such as non alcoholic fatty liver disease, the most prevalent liver disease worldwide. Most studies in this ...
Quintana Agustí, Mireia (Date of defense: 2019-09-30)
This thesis addresses three different subjects closely related. First, a phenotypic screening measuring cytotoxicity in the gastric cancer cell line HGC-27 is reported. Next, a targeted-based assay ...
Pérez Cano, Laura (Date of defense: 2013-06-28)
Computational methods are increasingly important to help to predict and characterize protein interactions. However, most of the efforts so far have focused on protein-protein and protein-ligand interactions, ...
Enciso Salas, Hilda Yuliana (Date of defense: 2017-09-22)
TP53INP2 es una proteína nuclear que activa la autofagia en moscas y células eucariotas. El propósito de esta tesis doctoral fue investigar si TP53INP2 modula la autofagia mitocondrial dependiente de ...
Rodríguez Nuevo, Aida (Date of defense: 2018-04-12)
Opa1 is a mitochondrial dynamics protein responsible for the fusion of the inner mitochondrial membrane, the maintenance of cristae morphology, and involved in mitochondrial DNA stability. In this study ...
Bidon-Chanal Badia, Axel (Date of defense: 2007-01-01)
La eficacia de un ligando en su interacción con una macromolécula biológica depende no solo de su capacidad para interaccionar de forma complementaria y específica con la constelación ...
Jiménez Panizo, Alba (Date of defense: 2021-12-14)
El receptor de glucocorticoides (GR) es un factor de transcripción que se expresa de forma ubicua y controla procesos esenciales para la vida como el metabolismo, la inflamación y la homeostasis. Aunque ...
García Castellanos, Raquel (Date of defense: 2006-04-18)
Esta tesis doctoral está centrada en el trabajo realizado sobre el regulador transcripcional de la resistencia a meticilina en Staphylococcus aureus, Mec1, y se ha concebido como la integración de tres ...
Moragas Garcia, Núria (Date of defense: 2021-02-26)
La teoria més plausible de l’evolució del càncer de mama és la que considera el carcinoma ductal in situ (DCIS) com a precursor no obligat del carcinoma ductal invasiu (IDC), que eventualment progressa ...
Romero Durana, Miguel Alfonso (Date of defense: 2018-11-26)
Proteins play a crucial role in virtually every biological process taking place within our cells. Most of the times, proteins do not participate in these processes alone but forming complexes of two or ...