Mostrando ítems 21-30 de 77
Frigolé Vivas, Marta (Fecha de defensa: 2020-09-23)
[eng] Drug discovery is the process by which new drugs are found and developed into the market. Given the scope of this thesis, the term “drug” will refer to small molecules and the term “target” to ...
Pons Pons, Alba (Fecha de defensa: 2021-12-16)
SLIMP (Seryl-tRNA Synthetase-Like Insect Mitochondrial Protein) was identified during the generation of a mitochondrial human disease fly model. SLIMP was described as a previously uncharacterized paralog ...
Tur Torres, Juan (Fecha de defensa: 2017-03-22)
Mitochondria are well known for their role as bioenergetic and biosynthetic organelles. Recently, they also have emerged as one of the main regulators of innate immune responses, mostly for its ability ...
López Martínez, Montserrat (Fecha de defensa: 2017-09-26)
Electron Transfer (ET) plays essential roles in crucial biological processes such as cell respiration and photosynthesis. It takes place between redox proteins and in protein complexes that display an ...
Díaz Perlas, Cristina (Fecha de defensa: 2018-03-07)
Peptides play a critical role in human physiology and harbour a huge potential as therapeutic agents. In this thesis, new peptides have been discovered as ligands for the epidermal growth factor (EGF) ...
Pallara, Chiara (Fecha de defensa: 2016-02-04)
Proteins are large biomolecules that play essential functional and structural roles within cells and that typically act through their interaction with other proteins and biomolecules, forming highly ...
Maíllo Carbajo, Carlos (Fecha de defensa: 2016-06-21)
The Cytoplasmic Polyadenylation Element Binding (CPEB)-family of RNA-binding proteins is composed of four paralogs in mammals, CPEB1-4. The CPEBs control the translation of the targeted mRNAs by modulating ...
Cuesta Borràs, Estefania (Fecha de defensa: 2019-11-28)
Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. ...
Ezquerra González, Artur (Fecha de defensa: 2019-06-27)
Microtubules (MTs) mediate a range of essential cellular processes including cell division, intracellular transport and organelle positioning, by forming specifically adapted arrays. Assembly, maintenance ...
Orellana, Laura (Fecha de defensa: 2014-05-30)
Protein structure, dynamics and function, are inseparable in order to understand the mechanisms of Life at the molecular level. From the structure comes dynamics, and from dynamics many, if not all, ...