Ara mostrant els elements 11-18 de 18
Oller Salvia, Benjamí (Data de defensa: 2015-05-18)
Brain delivery is a major unmet challenge because most drugs cannot cross the blood-brain barrier (BBB). Despite the restrictive nature of this barrier, brain vasculature reaches essentially every neural ...
Gordo Villoslada, Susana (Data de defensa: 2008-06-30)
Protein-protein interactions are essential in biological processes and thus, they have become very promising therapeutic targets. Nevertheless, the artificial modulation of protein complexes remains a ...
Le Roux, Anabel-Lise (Data de defensa: 2015-11-18)
c-Src is the leading member of the Src family of non-receptor tyrosine kinases, which are involved in many signaling pathways. Its deregulation affects cell migration, proliferation and survival. c-Src ...
Serra Vidal, Bernat (Data de defensa: 2014-05-27)
Alzheimer’s disease (AD) is a neurodegenerative disorder which major risk factor is age. Current drugs only offer symptomatic alleviation in AD, thus a disease-modifying treatment is urgent. The amyloid-β ...
Vila Farrés, Xavier (Data de defensa: 2014-11-14)
Nowadays in the world there is a very big problem associated with two factors related to each other. The first factor is the increase in the resistant of certain bacteria, especially the bacteria from ...
Guixer, Bernat (Data de defensa: 2014-03-31)
The blood-brain barrier (888) is a biological barrier that plays a crucial role protecting the brain from neurotoxic agents and regulating the influx and efflux of molecules required for the correct ...
Ciudad Fernández, Sonia (Data de defensa: 2016-11-08)
The present thesis is based on the work developed about the use of peptides and small proteins in protein surface molecular recognition. Peptides present several advantages when compared with small ...
Arranz Gibert, Pol (Data de defensa: 2017-01-12)
The work of this thesis is based on research on peptides able to cross the blood-brain barrier and their use as tools to enable the delivery of drugs into the brain. The blood-brain barrier (BBB) is ...