Gómez Aleza, Clara (Date of defense: 2021-10-25)
[spa] La vía de RANK juega un papel crucial en remodelación ósea, con un anticuerpo monoclonal (denosumab) contra el ligando de la vía de señalización (RANKL), actualmente usado en clínica contra la ...
Eto, Yoshiki (Date of defense: 2021-10-29)
[eng] In this thesis, two recombinant Pichia pastoris strains producing chimeric HPV-HIV L1P18 protein were constructed. One intracellularly produces the chimeric protein while the other secrets it. ...
Zhu, Kaichen (Date of defense: 2023-01-18)
[eng] The total amount of global information to be stored and computed is increasing exponentially since the beginning of the 21st century. The semiconductor industry made great efforts to push the ...
Cucarull Martínez, Blanca (Date of defense: 2021-11-25)
[eng] Hepatocellular carcinoma (HCC) is the most common liver cancer and currently the fourth cause of cancer-related death. Since its appearance, the multityrosine kinase inhibitor (MKI) sorafenib has ...
Blasco Agell, Lucas (Date of defense: 2021-11-25)
[eng] Parkinson’s disease (PD) is an incurable neurodegenerative disease characterized by the loss of neuromelanin (NM)-containing dopamine neurons in Substantia Nigra pars compacta (SNpc) and accumulation ...
Mayayo Vallverdú, Clara (Date of defense: 2021-11-29)
[eng] Cystinuria, with a worldwide prevalence estimated at 1:7000, is a rare inherited disease characterized by urine hyperexcretion of cystine and dibasic amino acids. Its clinical manifestation is ...
Santos Gómez, Ana (Date of defense: 2021-11-26)
[spa] Los receptores ionotrópicos de tipo N-metil-D-aspartato (NMDAR) son canales iónicos activados por glutamato que juegan un papel clave en la fisiología neuronal. Los avances en la secuenciación ...
Koehorst, Emma Agathe (Date of defense: 2022-06-17)
[spa] La distrofia miotónica tipo 1 (DM1) es un trastorno multisistémico, progresivo y no tratable con una expansión CTG en el gen DMPK que es la base de la patología. La compleja naturaleza ...
Aragó Belenguer, Marc (Date of defense: 2022-06-30)
[spa] La reprogramación metabólica es uno de los procesos que caracterizan el cancer. Estos cambios en el metabolismo de las células tumorales no solo permiten a las células obtener los metabolitos ...
López Molina, Laura (Date of defense: 2022-06-17)
[spa] La enfermedad de Huntington (EH) es una enfermedad neurodegenerativa hereditaria causada por la mutación de la huntingtina (mHtt) que ocasiona síntomas motores, cognitivos y psiquiátricos. La ...