Novoa Pardo, Eva Maria (Date of defense: 2012-12-20)
Gene translation is a central process in all cells, in which messenger RNA (mRNA) is decoded by the ribosome to produce a specific amino acid chain, that will later fold into an active protein. This ...
Antolin Fontes, Albert (Date of defense: 2019-03-07)
The mitochondrial Seryl-tRNA Synthetase (SerRS2) is a member of the class II tRNA synthetase family. The mature enzyme catalyses the ligation of serine to tRNASer in mitochondria. During the process of ...
Pons Pons, Alba (Date of defense: 2021-12-16)
SLIMP (Seryl-tRNA Synthetase-Like Insect Mitochondrial Protein) was identified during the generation of a mitochondrial human disease fly model. SLIMP was described as a previously uncharacterized paralog ...
Ros Simó, Enric (Date of defense: 2020-12-16)
The present doctoral thesis has been devoted to the use of 1,2,4,5-tetrazines as potential tools for chemical biology. Tetrazines have become extremely interesting functionalities due ...
Picchioni, Daria (Date of defense: 2014-10-23)
Our research group focuses on protein translation and more specifically on the mechanism of transfer RNA (tRNA) aminoacylation by a family of essential and universal enzymes called aminoacyl-tRNA ...
Guitart Rodés, Tanit (Date of defense: 2010-12-22)
Les aminoacil-ARNt sintetases (aaRS) són els enzims encarregats d'aminoacilar els ARN de transferència (ARNt) per tal que puguin ser utilitzats pels ribosomes en el procés de síntesi proteica. La síntesi ...
Roura Frigolé, Helena (Date of defense: 2018-07-27)
Adenosine deaminase acting on transfer RNA (ADAT) is a human heterodimeric enzyme that catalyzes the deamination of adenosine (A) to inosine (I) at the first position of the anticodon of transfer RNAs ...
Rodríguez Escribà, Marta (Date of defense: 2020-01-21)
Transfer RNAs (tRNAs) are key adaptor molecules that mediate decoding of messenger RNAs (mRNAs) into proteins by complementary pairing of their anticodons with mRNA codons. tRNAs that undergo adenosine ...
Rafels Ybern, Àlbert (Date of defense: 2018-07-17)
Inosine is a guanosine analogue that when is found at the wobble position of the tRNAs (I34) expands its codon recognition capability. Inosine can wobble pair with cytosine, adenosine and uridine. Because ...