Martínez-Quintanilla Martínez, Jordi (Date of defense: 2010-04-21)
El adenocarcinoma de páncreas y el cáncer de colon son una de las causas de muerte, relacionadas con el cáncer, más comunes en los países desarrollados. Los tratamientos convencionales para este tipo ...
Rodríguez García, Alba (Date of defense: 2015-02-27)
Oncolytic adenoviruses represent an appealing therapeutic approach to treat cancer regarding its capability to infect and kill selectively tumor cells without damaging normal tissues. Tumor targeting ...
Arias Badia, Marcel (Date of defense: 2017-09-29)
Oncolytic virotherapy with Adenoviruses has regained importance in the past years with the appearance of fresh and promising strategies to deal with tumors. Among the major limitations of this therapy ...
Guedán Carrió, Sònia (Date of defense: 2009-06-08)
Els adenovirus oncolítics són una estratègia molt prometedora pel tractament del càncer, però l'augment de la seva potència i dispersió intratumoral és imprescindible per tal que aquests vectors presentin ...
Puig Saus, Cristina (Date of defense: 2013-07-15)
La viroteràpia amb adenovirus oncolítics es basa en la lisi selectiva de la cèl•lula tumoral a través de la replicació viral. Les principals limitacions d’aquesta teràpia són: la limitada arribada del ...
Sostoa Pomés, Jana de (Date of defense: 2019-05-31)
Oncolytic virus (OV)-based therapies have an emerging role in the treatment of solid tumors, involving both direct cell lysis and immunogenic cell death. Nonetheless, tumor- associated stroma limits the ...
Fajardo Calderón, Carlos Alberto (Date of defense: 2017-05-19)
Oncolytic adenoviruses that selectively replicate in cancer cells while sparing normal tissue have gained considerable attention as novel anticancer drugs. However, clinical trials with these viruses ...
Rojas Expósito, Luis Alfonso (Date of defense: 2017-05-26)
Cancer virotherapy with oncolytic adenoviruses represents a promising therapeutic approach due to the capacity of these viruses to infect and selectively kill tumor cells without damaging normal tissues. ...
Farrera Sal, Martí (Date of defense: 2020-10-30)
The oncolytic viruses (OVs) preferentially infect tumor and selectively replicate in cancer cells without harming normal tissues. OVs have been tested in clinical trials as monotherapy or combined with ...