Crosas Molist, Eva (Date of defense: 2015-02-09)
Reactive oxygen species (ROS) are short-lived, highly electrophilic molecules generated by the partial reduction of oxygen to form superoxide, hydrogen peroxide and hydroxyl radical as well as other ...
Caja Puigsubirà, Laia (Date of defense: 2010-03-08)
En los últimos años nuestro grupo ha estudiado las diferentes vías de señalización inducidas por TGF-β en hepatocitos fetales de rata. A dosis bajas, el TGF-β inhibe el crecimiento, pero a ...
Moreno Càceres, Joaquim (Date of defense: 2016-01-18)
The transforming growth factor-beta (TGF-β) is a cytokine involved in many physiological and pathological processes. Its dual role has been described in the liver, where it can either induce pro- or ...
Cepeda, Edgar B. (Date of defense: 2015-12-18)
CXCR4 is a chemokine receptor originally discovered and cloned in leukocytes that functions by controling the migration to the inflammatory foci. The CXCR4 chemokine receptor and its ligand, SDF-1α (also ...
Mainez Villoro, Jessica (Date of defense: 2012-05-16)
In the last years our research has been focused on analyzing the signaling pathways induced by TGF-β in liver tumor cells, to understand the molecular mechanisms that confer resistance to its suppressor ...
López Luque, Judit (Date of defense: 2016-11-23)
Transforming growth factor-beta (TGF-β) is an important growth suppressor in hepatocytes, inhibiting proliferation and inducing cell death. However, it also plays a role in other processes such as ...
Caballero Díaz, Daniel (Date of defense: 2018-02-09)
Hepatocellular Carcinoma (HCC) is one of the most common cancers. During hepatocarcinogenesis (a multistep process) there is a disruption of the balance between cell death and survival signalling pathways, ...