Mostrando ítems 1-10 de 29
Yoldi, Guillermo (Fecha de defensa: 2018-10-23)
The discovery that RANK signaling mediates the protumorigenic role of progesterone in the mammary gland and its association with poor prognosis in breast cancer has opened the possibility of using RANKL ...
Herrera Camacho, Antonio (Fecha de defensa: 2015-11-06)
El meduloblastoma es un tumor cerebral maligno localizado en la fosa posterior del cráneo, con una muy alta incidencia en niños. Hasta cuatro distintos subgrupos de meduloblastomas pueden ser definidos ...
Zuazo Gaztelu, Iratxe (Fecha de defensa: 2018-11-23)
Tumor progression is a complex conundrum of events that involve not only tumor cells, but also their surrounding microenvironment. Accounting to the natural dependency of tumors on angiogenesis, its ...
Simón Extremera, Pilar (Fecha de defensa: 2017-05-12)
El carcinoma escamoso (SCC) es el segundo tumor de piel más frecuente en humanos caucásicos. Estudios recientes demuestran que el crecimiento tumoral es mantenido por una población de células tumorales, ...
Domostegui Fernández, Ana (Fecha de defensa: 2019-12-05)
The oncogene MYC is altered and its expression is deregulated in up to 70% of human cancers, including B cell neoplasms. Earlier studies in a mouse model of Eμ-MYC-driven B-cell lymphomas reported that ...
Méndiz Manero, Mª Victoria (Fecha de defensa: 2022-09-16)
[eng] I have used the brain tumours that originate in Drosophila larvae upon depletion of the brain tumor (brat) gene as a model to study neoplastic malignant growth. I have used genetic analysis to ...
Cortés Crignola, Constanza (Fecha de defensa: 2014-12-19)
Els neuroblastomes es caracteritzen per l’heterogeneïtat de les cèl•lules que els composen i la seva capacitat de transdiferenciar entre els diferents fenotips cel•lulars. La freqüència de mutacions ...
Meo Evoli, Nathalie (Fecha de defensa: 2014-07-07)
The oncogenic properties of E2F1 have been traditionally associated with the role of the oncogene in proliferation, but during the last few years many other functions associated with this family of ...
De Mol, Eva (Fecha de defensa: 2014-06-26)
Prostate cancer (PCa) is the second most common cancer in men after lung cancer. Around 1.1 million men worldwide were diagnosed with PCa in 2012. PCa depends essentially on androgen stimulation for ...
Balcells Nadal, Cristina (Fecha de defensa: 2019-12-19)
Metastasis and drug resistance represent the two main causes of therapeutic failure in oncology. In the present dissertation, the interplay between them has been interrogated using metabolomics, systems ...