Puigdellívol Cañadell, Maria del Mar (Date of defense: 2014-11-27)
Understanding the molecular underpinnings of neuronal dysfunction and degeneration involved in Huntington’s disease is a goal of increasing urgency for society and scientific community. In this Thesis ...
Anglada Huguet, Marta (Date of defense: 2013-07-22)
Huntington’s disease is a progressive neurodegenerative disorder caused by the expansion of a CAG tract in the exon-1 of the huntingtin gene. Mutant huntingtin induces a large amount of toxic effects ...
Rué Cabré, Laura (Date of defense: 2012-07-12)
La malaltia de Huntington és un trastorn neurodegeneratiu progressiu causat per una expansió de repeticions del triplet CAG (més de 37) en l’exó 1 del gen de la huntingtina que genera una proteïna ...
Cherubini, Marta (Date of defense: 2016-01-15)
Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder, characterized by progressive behavioral, motor and cognitive deficits (HDCRG, 1993; Ross & Margolis, 2001). The ...