Puigdellívol Cañadell, Maria del Mar (Date of defense: 2014-11-27)
Understanding the molecular underpinnings of neuronal dysfunction and degeneration involved in Huntington’s disease is a goal of increasing urgency for society and scientific community. In this Thesis ...
Pardo Muñoz, Mònica (Date of defense: 2015-11-12)
The striatum is one of the brain structures that controls body movement. In humans the striatum consists of two nuclei, the caudate and putamen which are separated by the internal capsule, while in mice ...
Anglada Huguet, Marta (Date of defense: 2013-07-22)
Huntington’s disease is a progressive neurodegenerative disorder caused by the expansion of a CAG tract in the exon-1 of the huntingtin gene. Mutant huntingtin induces a large amount of toxic effects ...
Cherubini, Marta (Date of defense: 2016-01-15)
Huntington's disease (HD) is an autosomal-dominant inherited neurodegenerative disorder, characterized by progressive behavioral, motor and cognitive deficits (HDCRG, 1993; Ross & Margolis, 2001). The ...