Atcher Ubiergo, Joan (Date of defense: 2015-07-28)
Dynamic combinatorial chemistry proposes the creation of a library of compounds (dynamic combinatorial library, DCL) inter-connected through reversible chemical processes. The concentrations in a DCL ...
Balaceanu, Alexandra (Date of defense: 2018-12-12)
1. The Force Field Accuracy Problem. The utility and applicability of MD simulations to model biomolecular systems goes only as far as its ability to sufficiently sample the conformational space and ...
Salmatonidis, Apostolos (Date of defense: 2019-09-30)
Exposure to nanoparticles has been associated with adverse effects on human health. When the exposure route is inhalation, nanoparticles can cause pulmonary inflammation which may be more severe than ...
Alagia, Adele (Date of defense: 2015-12-11)
To direct post-transcriptionally gene silencing, RNAi machinery exploits the formation of base pairs between the loaded guide strand and the complementary mRNA. The Ago2 protein is the “slicer” effector ...
Mendive Tapia, Lorena (Date of defense: 2017-02-17)
In the present thesis we have investigated the development of new methodologies for the selective and straightforward chemical modification of Trp amino acid either alone or in peptides. In the first ...
Vílchez Maldonado, Silvia (Date of defense: 2014-03-21)
El objetivo principal de la presente tesis es el diseño de nanopartículas de etilcelulosa para su utilización como vehículos de principios activos o sustancias lipofílicas y su deposición sobre un tejido, ...
Flores Rubio, Cintia (Date of defense: 2016-01-25)
En los últimos años, los contaminantes emergentes (ECs) están recibiendo una creciente atención debido a los efectos nocivos que suponen para los organismos vivos y al riesgo ambiental que representan. ...
Bazyaran, Fatemeh (Maryam) (Date of defense: 2019-04-01)
The main objective of this research work was to produce environmentally friendly cermets coatings, Ni and Co free matrix, alternative to conventional WC- Co, by thermal spray processes. WC-Co cermets ...
Font Ingles, Joan (Date of defense: 2017-06-09)
Pain is one of the main medical problems that in several cases results into a chronic disease with limited effective treatment, thus the discovery of new drugs to fight against constitutes a big challenge ...
Boleda Vall-llovera, Mª Rosa (Date of defense: 2015-11-23)
Les drogues d'abús i els fàrmacs estan considerats com contaminants d'interès emergent en el medi aquàtic, és a dir, són substàncies que no estan incloses en els programes habituals de control i ...