Ara mostrant els elements 51-60 de 174
Aulicino, Francesco (Data de defensa: 2016-12-15)
The adaptive response of cells to external stimuli is an intriguing mechanism at the basis of the existence of life itself. For this purpose, signalling pathways and gene regulatory networks elegantly ...
Comerma Blesa, Laura (Data de defensa: 2016-07-12)
We found that IgM+IgD- memory (ME-M) B cells formed a large reservoir of intestinal antigen-selected IgM+ lymphocytes distinct from antigen-naïve IgM+ lymphocytes. Human ME-M B cells colonized the ...
Sesé Ballesteros, Borja (Data de defensa: 2013-07-05)
Embryonic stem (ES) cells are able to differentiate into any cell type, a property called pluripotency, and have unlimited potential for self-renewal. Although the molecular mechanisms responsible for ...
García-Prat, Laura (Data de defensa: 2015-10-14)
During aging, muscle stem cell regenerative function declines, being maximal at advanced geriatric age, due to a quiescence-to-senescence transition. How quiescence is maintained over long periods of ...
Inglés Ferrándiz, Marta (Data de defensa: 2018-12-14)
In this thesis, we have been studying the role of UNR, and RNA-binding protein that regulates translation and/or stability of its targets. The functional relevance of UNR was studied in two different ...
Batlle Gómez, Raquel (Data de defensa: 2011-12-19)
The Snail1 transcriptional repressor is a key factor responsible in triggering epithelial to mesenchymal transition. Although Snail1 is widely expressed in early development, it is limited in adult ...
Nadimpalli, Hima Priyanka (Data de defensa: 2017-12-11)
Cytoplasmic polyadenylation is a widespread mechanism to control mRNA translation. In vertebrates, this mechanism requires two sequence elements in the 3’ UTR of substrate mRNAs, the U-rich Cytoplasmic ...
Di Mauro, Gianmarco (Data de defensa: 2019-02-28)
Dsk2/UBQLN is a conserved extraproteasomal ubiquitin receptor that has been widely described as a protein involved in the ubiquitin proteasome pathway. In Drosophila, this protein has been recently ...
Tilgner, Hagen (Data de defensa: 2011-06-02)
L’Splicing de les molècules d’ARN és el procés pel qual les seqüències interposades (“introns”) s’eliminen, i les seqüències restants es concatenen per a formar l’ARN madur. La investigació recent ...
Bascones Gleave, Sabrina (Data de defensa: 2016-12-20)
The spleen contains a unique subset of innate-like marginal zone (MZ) B cells that rapidly mount protective antibody responses to invasive encapsulated bacteria. Here we show that human splenic MZ B ...