Casadomé Burriel, Laura (Date of defense: 2005-03-01)
Yeast cells are exposed to a wide variety of environment stresses, among them changes in the osmotic conditions. An osmolar upshift leads to fast loose of intracellular water, so living cells have ...
Vogel González, Marina (Date of defense: 2021-09-03)
Zinc is an essential trace element with structural, catalytic and signaling roles in our body. At cellular level, zinc homeostasis participates in fundamental functions such as cell proliferation, ...
Carbonell Núñez, Caterina (Date of defense: 2016-12-19)
Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Activation of the p38 SAPK is critical to elicit the early gene ...
Altadill Balsells, Mireia (Date of defense: 2023-06-30)
Human cytomegalovirus (HCMV) causes a prevalent lifelong infection in all human populations. Although the course is generally mild and the virus remains latent, HCMV can cause severe disorders in ...
Martínez Ara, Guillermo (Date of defense: 2022-09-19)
During embryonic development, cellular forces synchronize in space and time to generate functional tissue shapes. Apical constriction is a force-generating process necessary to provoke the folding of ...
Häkkinen, Hanna-Maria (Date of defense: 2022-07-01)
Cellular errors can spontaneously occur during vertebrate embryo development and can lead to apoptosis. Recent work in our lab revealed a novel function of the embryonic epithelium as an efficient ...
Theka, Ilda (Date of defense: 2017-02-06)
Las células madre embrionarias (ESCs) derivan de la masa cellular interna de los blastocistos y son capaces de generar las tres capas germinales. Muchos factores controlan la pluripotencia incluyendo ...
Ferrando Martorell, Eva (Date of defense: 2015-11-10)
The activation of Notch1 receptor triggers differential outcomes depending on the upstream activating ligand. This way, Jag1-Notch1 activation promotes endothelial to hematopoietic transition process ...
Roset i Huguet, Ramon (Date of defense: 2008-04-04)
The aim of this thesis is the characterization of a protein involved in apoptosis. Our group has identified an early step common to different forms of intrinsic apoptosis stimuli. This step requires de ...
Lecland, Nicolas (Date of defense: 2014-04-10)
During mitotic spindle assembly, γ-tubulin ring complexes (γTuRCs) nucleate microtubules at the centrosome, around mitotic chromatin and, by augmindependent recruitment, from pre-existing microtubules. ...