Mostrando ítems 51-60 de 174
Pedone, Elisa (Fecha de defensa: 2014-12-16)
Mouse embryonic stem (ES) cells derived from the inner cell mass of the blastocyst can be maintained in culture, under pluripotent conditions, using Serum+LIF medium. However, it has been published that ...
Aulicino, Francesco (Fecha de defensa: 2016-12-15)
The adaptive response of cells to external stimuli is an intriguing mechanism at the basis of the existence of life itself. For this purpose, signalling pathways and gene regulatory networks elegantly ...
Comerma Blesa, Laura (Fecha de defensa: 2016-07-12)
We found that IgM+IgD- memory (ME-M) B cells formed a large reservoir of intestinal antigen-selected IgM+ lymphocytes distinct from antigen-naïve IgM+ lymphocytes. Human ME-M B cells colonized the ...
Sesé Ballesteros, Borja (Fecha de defensa: 2013-07-05)
Embryonic stem (ES) cells are able to differentiate into any cell type, a property called pluripotency, and have unlimited potential for self-renewal. Although the molecular mechanisms responsible for ...
García-Prat, Laura (Fecha de defensa: 2015-10-14)
During aging, muscle stem cell regenerative function declines, being maximal at advanced geriatric age, due to a quiescence-to-senescence transition. How quiescence is maintained over long periods of ...
Inglés Ferrándiz, Marta (Fecha de defensa: 2018-12-14)
In this thesis, we have been studying the role of UNR, and RNA-binding protein that regulates translation and/or stability of its targets. The functional relevance of UNR was studied in two different ...
Batlle Gómez, Raquel (Fecha de defensa: 2011-12-19)
The Snail1 transcriptional repressor is a key factor responsible in triggering epithelial to mesenchymal transition. Although Snail1 is widely expressed in early development, it is limited in adult ...
Nadimpalli, Hima Priyanka (Fecha de defensa: 2017-12-11)
Cytoplasmic polyadenylation is a widespread mechanism to control mRNA translation. In vertebrates, this mechanism requires two sequence elements in the 3’ UTR of substrate mRNAs, the U-rich Cytoplasmic ...
Di Mauro, Gianmarco (Fecha de defensa: 2019-02-28)
Dsk2/UBQLN is a conserved extraproteasomal ubiquitin receptor that has been widely described as a protein involved in the ubiquitin proteasome pathway. In Drosophila, this protein has been recently ...
Tilgner, Hagen (Fecha de defensa: 2011-06-02)
L’Splicing de les molècules d’ARN és el procés pel qual les seqüències interposades (“introns”) s’eliminen, i les seqüències restants es concatenen per a formar l’ARN madur. La investigació recent ...