Janich, Peggy (Date of defense: 2012-02-16)
The natural daily cycles of light and dark have played a fundamental role in shaping the development of an adaptive intrinsic clock mechanism which allows organisms to coord ...
Martínez García, Antonio (Date of defense: 2019-12-09)
I joined the lab of Dra. Pura Muñoz to study the capacity of self-repair of skeletal muscle after an acute injury. During this process many different cell types interact to coordinate and regulate muscle ...
Lioutas, Antonio (Date of defense: 2012-11-09)
Aurora A (AurA) is an important mitotic kinase mainly studied for its involvement in cell cycle progression, centrosome maturation, mitotic spindle pole organization and bipolar spindle formation. ...
Sancho Medina, Mònica (Date of defense: 2008-05-30)
At least eleven histone H1 variants exist in mammalian somatic cells that bind to the linker DNA and stabilize the nucleosome particle contributing to higher order chromatin compaction. In addition of ...
Grippa, Alexandra (Date of defense: 2015-06-12)
Most cells store energy in lipid droplets (LDs), specialized storage organelles composed of a neutral lipid core that, during their biogenesis, is packaged into a single phospholipid monolayer decorated ...
Plana Carmona, Marcos (Date of defense: 2021-03-17)
Continuous C/EBPa expression converts B cells into macrophages while its transient upregulation before the Yamanaka factors yields highly efficient iPSC reprogramming. C/EBP members regulate Il6 ...
Khan, Abdul Kareem (Date of defense: 2009-03-05)
La preorganització electrostàtica del centre actiu s'ha postulat com el mecanisme genèric de l'acció dels enzims. Així, alguns residus "estratègics" es disposarien per catalitzar reaccions interaccionant ...
Pareja Gómez, Josep (Date of defense: 2010-11-22)
Pluripotent cells are unique due to their developmental potential and the possibility to study them is the key step to understand human development. These cells are characterized by their ability to ...
Traveset Martínez, Laia (Date of defense: 2020-10-30)
Maintenance of steady-state and stress-adapted hematopoiesis depends on the fitness of hematopoietic stem and progenitor cells (HSPCs) in the bone marrow. Hematopoietic stem cells (HSCs) can adapt to ...
Isús Díaz, Laura (Date of defense: 2017-02-13)
Since the advent of the genomic era, vast amounts of data from heterogeneous biomedical sources have been generated, revealing an overwhelming complexity and creating a need for new computational tools. ...