Ruiz Martínez, Santiago (Date of defense: 2016-07-08)
The main aim of the present study is to characterize the biological and biophysical properties of Apoptin, a viral protein that selectively induces apoptosis of a wide range of tumor cells. Apoptin has ...
Buján Murlà, Núria (Date of defense: 2016-01-29)
The diagnose of a mitochondrial disease implies biochemical studies such as the enzymatic activities of the mitochondrial respiratory chain (MRC) and the quantification of the amount of CoQ10 in energetic ...
Balmaña Esteban, Meritxell (Date of defense: 2016-07-07)
Cancer is one of the leading causes of death worldwide. Pancreatic ductal adenocarcinoma (PDAC) is characterized by high intrinsic aggressiveness and late diagnosis, causing poor prognosis and resulting ...
García Galindo, Glòria (Date of defense: 2016-07-19)
Les ribonucleases són enzims que presenten citotoxicitat selectiva per a cèl·lules tumorals. S'ha proposat l’ús de ribonucleases dirigides a nucli (ND-RNases) com a fàrmacs antitumorals. En aquest treball ...