Vert Company, Anna (Date of defense: 2014-07-30)
Cytotoxic ribonucleases are promising agents to be used in the treatment of cancer. Our group previously described a cytotoxic human pancreatic ribonuclease variant, named PE5, which carries a nuclear ...
Bassagañas i Puigdemont, Sònia (Date of defense: 2014-12-03)
Changes in the expression of Lewis-type glycan antigens, especially a predominance of sialyl-Lewis x (SLex) structure, and the glycosyltransferases involved in its synthesis, correlate with pancreatic ...
Carrion-Salip, Dolors (Date of defense: 2014-09-17)
Most current chemotherapeutic agents are of limited use due to their side effects and the resistance to treatment that tumour cells develop. In this thesis, we have contributed to the knowledge of these ...
Soler Campmajó, David (Date of defense: 2014-10-30)
Les inteïnes són dominis proteics que mitjançant un procés de tall i unió s’autoescindeixen de la cadena polipeptídica precursora i catalitzen la unió de les seqüències flanquejants (exteïnes) mitjançant ...