Mostrando ítems 1-10 de 14
Rosselló Tortella, Margalida (Fecha de defensa: 2021-12-09)
Transfer RNAs (tRNAs) are essential molecules that allow the translation of the genetic code into amino acids. Extensive research during the last 50 years have revealed that, despite their apparently ...
Szczesna, Karolina (Fecha de defensa: 2014-09-26)
INTRODUCTION: In 1966, Rett syndrome (RTT, OMIM#312750) was for the first time described as a clinical issue by Dr. Andreas Rett, an Austrian pediatrician. He has observed in 22 patients similar ...
Pérez Salvia, Montserrat (Fecha de defensa: 2019-03-01)
Cancer is considered nowadays a genetic and epigenetic disease. Aberrancies in epigenetic marks in DNA and histone tails together with alterations in epigenetic regulators responsible of catalyzing ...
Duran Ferrer, Martí (Fecha de defensa: 2020-11-19)
The DNA from our cells carries the genetic information to build a human being. This information is interpreted through epigenetic marks that lead to tightly coordinated and cell type-specific gene ...
Oliveira Mateos, Cristina (Fecha de defensa: 2020-06-16)
The vast majority of the human genome is transcribed giving rise to non-coding RNAs. Antisense transcripts are one of the most abundant types of long non-coding RNAs and many of them have regulatory ...
Rodríguez Cortez, Virginia Carolina (Fecha de defensa: 2015-02-06)
The proper function of the immune system requires complex regulatory mechanisms and a highly strict balance in the amount and function of immune and non-immune elements. Part of the primary immunodeficiencies ...
Moreta Moraleda, Cristina (Fecha de defensa: 2022-01-25)
The hypothesis of the present thesis is that the presence or absence of some chromatin factors may facilitate or impair the action of chemotherapeutic drugs in colorectal cancer (CRC). Chromatin factors ...
Mira Martínez, Sofía (Fecha de defensa: 2018-02-23)
Malaria is responsible of almost half a million deaths every year. Currently, campaigns for the control and elimination of malaria are implemented in malaria endemic areas. However, drug resistance is ...
Ortiz Barahona, Vanessa (Fecha de defensa: 2022-04-01)
The general aim of this thesis is to identify and characterize if there are DNA methylation patterns giving rise to cancer-related m5C RNA modification defects, potentially promoting malignant transformation ...
Lorente-Sorolla Martínez-Acítores, Clara (Fecha de defensa: 2019-12-20)
This doctoral thesis describes the participation of epigenetic mechanisms, and more specifically DNA methylation, in innate immune responses against pathogens. Innate immunity is the first barrier of ...
616 - Patología. Medicina clínica. Oncología (6)
575 - Genética general. Citogenética general. Inmunogenética. Evolución. Filogenia (3)
577 - Bioquímica. Biología molecular. Biofísica (2)
616.9 - Enfermedades infecciosas y contagiosas. Fiebres (2)