Departament de Ciències Mèdiques: Recent submissions
Now showing items 61-80 of 114
Estudi epidemiològic poblacional de la incidència, tendència i supervivència de les neoplàsies limfoides a la província de Girona durant un període de 20 anys (1996-2015)
The incidence, time trends and survival of lymphoid neoplasm’s in the Girona province are analyzed from 1996 to 2015. The survival of diffuse large B-cell lymphoma (LBDCG) before and after 2004 and estimate incidence rate ...
Avaluació de la funció renal en la millora de la predicció del risc vascular. Anàlisi del rol de les estatines en la prevenció primària d’esdeveniments cardiovasculars en la població amb malaltia renal crònica inicial
Cardiovascular diseases are the leading cause of mortality and morbidity worldwide as well as in our population. One of the main cardiovascular prevention strategies is to identify healthy patients who are at risk of ...
Estimación de la prevalencia de la hipercolesterolemia familiar y de las características clínicas asociadas en Cataluña
Familial hypercholesterolemia (FH) is the most frequent hereditary cause of premature coronary heart disease. The aim of this doctoral thesis is to determine the prevalence of subjects with FH phenotype (FH-P); to describe ...
El síndrome coronario agudo: tendencias en la magnitud del problema, en el manejo hospitalario y en la aparición de complicaciones en un estudio de base poblacional, y mejoras en las estrategias de prevención individual
Acute myocardial infarction incidence rates are very high in those over 74, with a tendency to decrease in recent years in men and are always higher in men than in women. Mortality rates over the age of 74 are very high. ...
Projecte “Girona Territori Cardioprotegit”: avaluació del funcionament dels desfibril·ladors públics
Introduction and aims: In recent years, public access defibrillation programs have exponentially increased the availability of automatic external defibrillators in public spaces but there are no data on their performance ...
Validesa del Sistema d’Informació pel Desenvolupament de la Investigació a Atenció Primària en l'estudi de malalties vasculars i estudi de l'efectivitat de les estatines en la reducció de mortalitat i malalties vasculars en la població major de 74 anys
Electronic Health Record are legal documents where all the bio-psycho-social information of care received by the healthcare system is recorded throughout their lives. The first causes of death in Spain are cardiovascular ...
Efectes de l’exercici de resistència de baixa intensitat i del suport nutricional sobre la sarcopènia i la inflamació crònica de baix grau en persones de 60-75 anys
Sarcopenia is a multifactorial entity characterized by loss of muscle mass, strength and functionality. People with sarcopenia are more at risk of developing insulin resistance, type 2 diabetes and excess fat in the muscle ...
Avaluació de la utilitat del monitoratge farmacocinètic dels fàrmacs anti-TNF en pacients amb malaltia inflamatòria intestinal en dos hospitals amb diferent grau d’especialització
The tumor necrosis factor (TNF) acts as a potent inducer of inflammation in autoimmune diseases like Crohn disease and ulcerative colitis. Current available treatments are based on TNF inhibition such as infliximab and ...
Creació i validació d'un model de predicció per al càlcul del temps d'angioplàstia primària en pacients amb infart agut de miocardi que són traslladats a un hospital amb disponibilitat d'hemodinàmica
Introduction: Achieving optimal times of reperfusion in STEMI patients transferred for primary percutaneos coronary intervention (PCI) remains a challenge, particularly in geographically disperse regions. Our goal was to ...
Estudio descriptivo y análisis de factores implicados en los casos de muerte producidos durante la práctica de buceo con escafandra autónoma (scuba)
SCUBA (self-contained underwater breathing apparatus) diving is an underwater activity that is practiced with a certain frequency in certain environments and which is very popular nowadays. In this thesis it is proved that ...
Estimación de la ingesta de sodio mediante una muestra de orina aislada frente a la orina de 24 horas. Desarrollo de un método de estimación y estudio de validación en muestras aleatorias
The sodium in 24H urine is the standard to quantify the intake. The objective is to develop a method to stimate using isolated urine sample, analyze the reliability, concordance and clinical utility. Observational, ...
La relación beneficio-riesgo del tratamiento farmacológico para la enfermedad de Alzheimer
The evidence available in the medical literature is conclusive that the risk-benefit relationship of the current medications for Alzheimer's disease is not favourable. This risk-benefit relationship is not significantly ...
DNA methylome in HER2-positive resistant breast cancer
The major clinical problem for HER2+ breast cancer target therapies is the acquisition of resistance. The DNA methylation status of the promoter gene region has been described as a common epigenetic alteration for ...
Influencia de la grasa epicárdica en la arritmia: fibrilación auricular, la cardioversión eléctrica, la recurrencia y el tratamiento
The thickness of epicartic fat can be directly measured by transthoracic echocardiography. Epicartic fat has recently been associated with the onset of atrial fibrillation (AF). In this work we will analyze the relationship ...
Therapeutic potential of pituitary adenylate cyclase-activating polypeptide and epigallocatechin gallate in motor and cognitive deficits of Huntington's disease models
Huntington's disease (MH) is a progressive neurodegenerative disorder characterized by a motor dysfunction, cognitive impairment, and psychiatric symptoms. At neuropathological level, it has been described that cognitive ...
Muerte súbita natural inexplicada: valor de la investigación genética post mortem
Natural death defines the death primarily attributed to an illness or an internal malfunction of the body, and not directly influenced by external forces. Most causes can be identified directly with macroscopic forensic ...
Regulome-seq: a novel approach for the identification of non-coding variants associated with human disease. Assessment of its applicability in 89 Brugada syndrome individuals
Brugada syndrome (BrS) is a cardiac electrical disease with high susceptibility to sudden cardiac death. Approximately 25-30% of BrS patients are explained by pathogenic variants in coding sequences of cardiac ion channels, ...
Factors associated with arterial stiffness in a general Mediterranean population and in a Mediterranean intermediate cardiovascular risk population
The objectives of the thesis are to estimate the prevalence of pathological arterial stiffness (measured with the Cardio-Ankle Vascular Index –CAVI-) in a general Mediterranean population and in a Mediterranean intermediate ...
Factors associats a la incidència de fibril·lació auricular i estudi de l'associació del tractament amb estatines amb la incidència d'aquesta arítmia en població hipertensa sense antecedents de malaltia isquèmica vascular
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and implies a huge social, medical, and economical burden. Analyses of AF risk factors in certain groups of population would allow tailored ...
WNT5A, SFRP5 y CRTC3: nuevas adipocinas relacionadas con la obesidad en la edad pediátrica
WNT5A is a protein with proinflammatory properties recently related to insulin resistance. It is believed that this protein might be regulated by SFRP5, which sequesters WNT5A exerting its anti-inflammatory actions and ...
