Now showing items 24-43 of 85
Kennington, Stuart (Date of defense: 2020-12-21)
This thesis focuses on the search for new methodologies for the direct, stereoselective and catalytic formation of carbon-carbon bonds through the formation of chiral nickel(II) enolate species and the application of such ...
Bonelli Blasco, Joaquin Daniel (Date of defense: 2022-12-14)
[eng] Nanomedicine is one of the cutting-edge fields in most of medical applications, specially, in oncology. The possibility to selectively vehiculize and specifically release a wide range of anticancer compounds gained ...
Presa i Rodríguez, Andreu (Date of defense: 2016-12-16)
The photoactivation of metal complexes with potential anticancer activity is a hot topic of current research, as it may lead to the development of more selective and efficient drugs. Photoactivated chemotherapy (PACT) with ...
Velasco Amigó, Verónica (Date of defense: 2016-10-28)
Desde hace años la ciencia del magnetismo ha centrado uno de sus objetivos más ambiciosos en el estudio y creación de dispositivos funcionales a escala molecular. Un ejemplo es el intento de implementación de la computación ...
Iruela Martin, Guillermo (Date of defense: 2021-09-16)
c-Src tyrosine kinase is associated with poor prognosis in many cancer processes. Although inhibitors of c-Src kinase activity are known, they have not reached success in clinical trials because of lack of selectivity or ...
Pérez Palau, Marina (Date of defense: 2022-07-08)
This thesis consists in the development of a new methodology of α-alkylation of carbonyl compounds and its application to the synthesis of small molecules with therapeutic interest. In this context, the alkylation of ...
Aguiló Linares, Elisabet (Date of defense: 2017-04-28)
Hace unos años, en el grupo de investigación donde se ha realizado esta Tesis Doctoral, se estudió un sistema de oro(I)-alquinilo con una fosfina soluble en agua, que dio lugar a la formación de un hidrogel. Este ejemplo ...
Castro-Alvarez, Alejandro (Date of defense: 2018-06-25)
El siguiente trabajo recopila los resultados conseguidos durante el transcurso del periodo Doctoral, el cual se divide en dos secciones: la primera sección aborda distintos estudios sobre reacciones organocatalíticas, ...
Falceto Palacín, Andrés (Date of defense: 2016-12-12)
En esta tesis se abordan diferentes problemas químicos relacionados con situaciones inusuales de enlace en moléculas. Para algunos de estos problemas se ha aplicado el análisis de pseudosimetría de los orbitales moleculares, ...
Vázquez Valero, Marta (Date of defense: 2016-07-22)
El uso de complejos inertes de metales de transición en procesos en los que se involucran moléculas biológicamente relevantes es un sistema ampliamente estudiado en la actualidad. El ejemplo a destacar de estos estudios ...
Romo Islas, Guillermo (Date of defense: 2023-07-14)
[eng] This thesis is mainly focused on studying the photophysical properties of Au(I), Ag(I), Cu(I), and Pt(II) coordinated compounds. This work can be divided into two parts: on the one hand, the compounds of the group ...
Pascual i Pérez, Marina (Date of defense: 2023-11-10)
[eng] Multidrug resistant bacteria have grown to be a significant medical concern as a result of decades of excessive antibiotic usage and overuse in human medicine, agriculture, and the animal industry. In this context, ...
Caparrós Rodríguez, Francisco Javier (Date of defense: 2018-07-06)
Les nanopartícules de metalls nobles han atret l’interès dels investigadors en els últims anys degut a la seva elevada activitat i selectivitat en un gran nombre de reaccions catalítiques. No obstant això, les nanopartícules ...
Mohammad Jabeen, Irrem Laareb (Date of defense: 2021-09-23)
c-Src is a non-receptor tyrosine kinase that controls numerous cellular signaling pathways. c-Src implication in human cancers was brought into the attention in the 1980s. Since its discovery, unveiling of c-Src ...
Maxwell Villacorta, Lindley Andrés (Date of defense: 2017-06-16)
En la primera parte de esta tesis, se basó en la síntesis de ligandos basados en la heptazina y los complejos formados con CuII. Utilizando 2-dipiridilamina para funcionalizar el núcleo de heptazina, (ligando que presenta ...
Pinto Martínez, Andrea (Date of defense: 2021-11-05)
During the last years, the research group where this Doctoral Thesis has been carried out has been pioneer in the development of different gold(I) complexes and resulting supramolecular assemblages with a wide variety of ...
Cerdeiras Montero, Elena (Date of defense: 2016-11-17)
Los materiales piezoeléctricos basados en el titanato zirconato de plomo (PZT) son ampliamente utilizados en una gran cantidad de dispositivos electrónicos debido a sus excelentes propiedades eléctricas. Esta mejora de las ...
Coines Lopez-Nieto, Juan (Date of defense: 2021-01-20)
Carbohydrates are essential molecules in biotechnology and for the proper functioning of living organisms. They are involved in energy storage, being structural components or participating in crucial biological processes ...
Martín Rodríguez, Alejandro (Date of defense: 2021-09-15)
In this doctoral thesis a series of computational and experimental studies of molecular magnetoresistance devices at room temperature is presented. This sort of devices is included in the molecular electronics framework ...
Cuscó Marigó, Cristina (Date of defense: 2018-03-22)
The Thesis is based on the development of a potentially-scalable methodology to prepare polyurethane/polyurea polymers to nanoencapsulate bioactive molecules. In the first part of the project, the design, optimization and ...