Now showing items 29-48 of 85

    Enolates Go Radical. Stereoselective Radical Alkylation Reactions of Titanium Enolates from N-Acyl Oxazolidinones with Carboxylic Acid Derivatives. Synthesis of Umuravumbolide 

    Pérez Palau, Marina (Date of defense: 2022-07-08)

    This thesis consists in the development of a new methodology of α-alkylation of carbonyl compounds and its application to the synthesis of small molecules with therapeutic interest. In this context, the alkylation of ...

    Estructuras supramoleculares de oro(I) con propiedades luminiscentes. Estudios de agregación y aplicaciones 

    Aguiló Linares, Elisabet (Date of defense: 2017-04-28)

    Hace unos años, en el grupo de investigación donde se ha realizado esta Tesis Doctoral, se estudió un sistema de oro(I)-alquinilo con una fosfina soluble en agua, que dio lugar a la formación de un hidrogel. Este ejemplo ...

    Estudio computacional de reacciones organocatalíticas e interacciones de macrólidos-proteínas del citoesqueleto 

    Castro-Alvarez, Alejandro (Date of defense: 2018-06-25)

    El siguiente trabajo recopila los resultados conseguidos durante el transcurso del periodo Doctoral, el cual se divide en dos secciones: la primera sección aborda distintos estudios sobre reacciones organocatalíticas, ...

    Estudio teórico de enlaces no clásicos 

    Falceto Palacín, Andrés (Date of defense: 2016-12-12)

    En esta tesis se abordan diferentes problemas químicos relacionados con situaciones inusuales de enlace en moléculas. Para algunos de estos problemas se ha aplicado el análisis de pseudosimetría de los orbitales moleculares, ...

    Estudio cinético de la interacción de complejos de metales de transición con moléculas biológicamente relevantes  

    Vázquez Valero, Marta (Date of defense: 2016-07-22)

    El uso de complejos inertes de metales de transición en procesos en los que se involucran moléculas biológicamente relevantes es un sistema ampliamente estudiado en la actualidad. El ejemplo a destacar de estos estudios ...

    Exploring the heavy atom effect and supramolecular assemblies of Au(I) and Pt(II) complexes 

    Romo Islas, Guillermo (Date of defense: 2023-07-14)

    [eng] This thesis is mainly focused on studying the photophysical properties of Au(I), Ag(I), Cu(I), and Pt(II) coordinated compounds. This work can be divided into two parts: on the one hand, the compounds of the group ...

    Fighting bacteria. Synthesis and study of Polymyxin derivates to improve their therapeutic properties 

    Pascual i Pérez, Marina (Date of defense: 2023-11-10)

    [eng] Multidrug resistant bacteria have grown to be a significant medical concern as a result of decades of excessive antibiotic usage and overuse in human medicine, agriculture, and the animal industry. In this context, ...

    Immobilització d’àtoms aïllats i nanopartícules de Pd sobre magnetita. Comportament catalític 

    Caparrós Rodríguez, Francisco Javier (Date of defense: 2018-07-06)

    Les nanopartícules de metalls nobles han atret l’interès dels investigadors en els últims anys degut a la seva elevada activitat i selectivitat en un gran nombre de reaccions catalítiques. No obstant això, les nanopartícules ...

    Insights into the myristoylated c-Src N-terminal Regulatory Element 

    Mohammad Jabeen, Irrem Laareb (Date of defense: 2021-09-23)

    c-Src is a non-receptor tyrosine kinase that controls numerous cellular signaling pathways. c-Src implication in human cancers was brought into the attention in the 1980s. Since its discovery, unveiling of c-Src ...

    Ligandos Supramoleculares en Complejos Metálicos con Propiedades Físicas Relevantes 

    Maxwell Villacorta, Lindley Andrés (Date of defense: 2017-06-16)

    En la primera parte de esta tesis, se basó en la síntesis de ligandos basados en la heptazina y los complejos formados con CuII. Utilizando 2-dipiridilamina para funcionalizar el núcleo de heptazina, (ligando que presenta ...

    Luminescent gold(I) supramolecular assemblies on materials and biological chemistry 

    Pinto Martínez, Andrea (Date of defense: 2021-11-05)

    During the last years, the research group where this Doctoral Thesis has been carried out has been pioneer in the development of different gold(I) complexes and resulting supramolecular assemblages with a wide variety of ...

    Materiales piezoeléctricos derivados del (Bi0,5Na0,5)TiO3-BaTiO3 : preparación y estudio de las propiedades funcionales 

    Cerdeiras Montero, Elena (Date of defense: 2016-11-17)

    Los materiales piezoeléctricos basados en el titanato zirconato de plomo (PZT) son ampliamente utilizados en una gran cantidad de dispositivos electrónicos debido a sus excelentes propiedades eléctricas. Esta mejora de las ...

    Mechanistic insights into substrate-assisted catalysis in glycosidases by means of QM/MM molecular dynamics 

    Coines Lopez-Nieto, Juan (Date of defense: 2021-01-20)

    Carbohydrates are essential molecules in biotechnology and for the proper functioning of living organisms. They are involved in energy storage, being structural components or participating in crucial biological processes ...

    Molecular-based Magnetoresistance Devices at Room Temperature 

    Martín Rodríguez, Alejandro (Date of defense: 2021-09-15)

    In this doctoral thesis a series of computational and experimental studies of molecular magnetoresistance devices at room temperature is presented. This sort of devices is included in the molecular electronics framework ...

    Multisensitive polyurethane/polyurea nanocapsules for smart drug delivery 

    Cuscó Marigó, Cristina (Date of defense: 2018-03-22)

    The Thesis is based on the development of a potentially-scalable methodology to prepare polyurethane/polyurea polymers to nanoencapsulate bioactive molecules. In the first part of the project, the design, optimization and ...

    New Catalytic Methods for Pauson-Khand Reactions, Isomerization and Asymmetric Hydrogenations. Application to the Synthesis of Bioactive Compounds 

    Cabré Montesinos, Albert (Date of defense: 2020-01-31)

    The main contribution of this doctoral thesis has been devoted to the field of synthetic organic chemistry. The Pauson-Khand reaction (PKR) is a metal-catalyzed [2+2+1] cycloaddition between an alkyne, an alkene and a ...

    New organic semiconductors based on the carbazole core: synthesis and application in optoelectronic devices 

    Bujaldón Carbó, Roger (Date of defense: 2022-11-22)

    [eng] The increasing demand on next-generation displays encourages an exhaustive research on the development of new and enhanced semiconductors. Apart from the conventional inorganic materials, organic-based semiconductors ...

    Ni-based catalysts for H2 production from ethanol steam reforming: Effect of the support and use of CO2 as regenerating agent and reactant 

    Bednarczuk, Lukasz (Date of defense: 2017-01-11)

    In this work, the effect of CO2 on the hydrogen production under substoichiometric ethanol steam reforming (ESR) conditions over nickel based catalysts was studied. A special emphasis was focused on the application of ...

    Nova síntesi d'interès industrial d'un fàrmac genèric 

    Tolrà Rovira, Roser (Date of defense: 2017-07-21)

    L'objectiu principal d'aquesta Tesi doctoral ha estat l’obtenció d’una via alternativa a les existents per a l'obtenció d'un intermedi clau, 1, en la síntesi d'un fàrmac anticoagulant. La nova via havia de ser novedosa i ...

    Novel antimicrobial peptides for therapeutic applications: design, synthesis, characterization, and evaluation of their biological and biophysical activity 

    Segovia Laserna, Rosario (Date of defense: 2022-03-08)

    After decades of exorbitant antibiotic misuse and overuse in human medicine, agriculture and livestock industry, multidrug resistant bacteria (MDR) have become a major medical concern. In this regard, the design of new, ...