Now showing items 15-19 of 19

    Relació estructura-funció de les proteïnes implicades en la leucoencefalopatia megalencefàlica amb quists subcorticals 

    Xicoy Espaulella, Efren (Date of defense: 2021-12-17)

    La Leucoencefalopatia Megalencefàlica amb Quists subcorticals (de l’anglès Megalencephalic Leukoencephalopathy with subcortical Cysts, MLC) és un tipus rar de leucodistròfia caracteritzada per la presència de vacuoles en ...

    Targeting mitochondrial metabolism in cancer: development and validation of PEPCK-M and PYCR1 inhibitors 

    Aragó Belenguer, Marc (Date of defense: 2022-06-30)

    [spa] La reprogramación metabólica es uno de los procesos que caracterizan el cancer. Estos cambios en el metabolismo de las células tumorales no solo permiten a las células obtener los metabolitos necesarios para su ...

    Unveiling novel components of the protein complex responsible for cGMP synthesis in retinal photoreceptors: role in cell physiology and disease 

    López Begines, Santiago (Date of defense: 2016-11-18)

    In photoreceptor cells of the retina, light triggers a protein G-mediated enzymatic cascade that leads to hydrolysis of cGMP. The drop in cGMP levels causes the closure of cGMP-channel at the plasma membrane, decreasing ...

    Vestibular Damage and Repair in Chronic Ototoxicity: Cellular Stages, Physiological Deficits and Molecular Mechanisms 

    Greguske, Erin A. (Date of defense: 2019-07-11)

    Progressive ototoxicity of the inner ear is prevalent in patients administered aminoglycoside antibiotics with little understanding of how this damage occurs and to what extent it can be recovered. Numerous in vitro and ...

    White adipose tissue characterization and lipid profiling in obesity 

    Dahdah, Norma (Date of defense: 2022-07-27)

    [eng] Obesity has become exceedingly pervasive, a resultant of amplified food availability and reshaped human behavior stimulated by urbanization. It poses as a major challenge for human metabolic physiology testing ...