Jora, Beatrice Elena (Date of defense: 2022-10-27)
[eng] The present thesis focuses on the study and synthesis of three active principles (APIs) with therapeutic activity. Although these compounds are commercially available, their route of synthesis are ...
Cañellas Santos, Mariona (Date of defense: 2022-11-03)
[eng] This industrial Ph.D. thesis aimed to illustrate the presence of the cell-based bioassays throughout the whole life of a drug product and to demonstrate its importance for a complete characterization ...
Bouzón Arnáiz, Inés (Date of defense: 2022-11-11)
[eng] Malaria caused 241 million cases and 627,000 deaths worldwide in 2020, representing one of the biggest threats for global health nowadays. The currently available arsenal of antimalarial drugs is ...
Laveriano Santos, Emily Pilar (Date of defense: 2022-11-29)
[eng] The rising of cardiometabolic risk factors like obesity, higher blood pressure, and alteration in the metabolism of lipids and glucose during adolescence increase the risk of type 2 diabetes ...
Pérez Calm, Adrià (Date of defense: 2023-07-28)
[eng] This thesis addresses molecular segregation in perylene-based systems, including lyotropic chromonic liquid crystals and water-in-water emulsions. These systems offer several advantages compared ...
Amorós-Galicia, Lola (Date of defense: 2023-02-08)
[eng] Sunscreen application is one of the best methods to prevent erythema, keratogenic cancer, melanoma and premature skin ageing. UV filters are the active substances preventing the harmful effects. ...
Duran Corbera, Anna (Date of defense: 2022-04-22)
G protein-coupled receptors (GPCRs) are a large family of membrane proteins responsible for signaling transduction processes. Due to their roles in modulating essential physiological functions, GPCRs ...
Folle, Camila (Date of defense: 2021-11-26)
The skin is major organ of the human body, and its function is to protect the internal tissue from environmental changes, maintains the body temperature and avoid penetration of contaminants. Therefore, ...
Martín López, Juan (Date of defense: 2022-07-15)
The present Thesis is divided in three chapters: 1. Design and synthesis of new soluble epoxide hydrolase inhibitors (sEHI) The synthesis of new soluble epoxide hydrolase inhibitors based on ureas ...
Alqahtani, Abdulateef (Date of defense: 2023-10-25)
[eng] In 2001, the initial hypothesis of targeted protein degradation (TPD) was born to announce the launching of a new era of therapeutics development not by inhibiting a component of ubiquitin-proteasome ...