Folle, Camila (Date of defense: 2021-11-26)
The skin is major organ of the human body, and its function is to protect the internal tissue from environmental changes, maintains the body temperature and avoid penetration of contaminants. Therefore, ...
Szura, Arkadiusz Damian (Date of defense: 2023-03-17)
[eng] The emergence and spread of antibiotic resistance among bacteria has become an undisputed global problem and one of the greatest threats to public health in the 21st century. The widespread, ...
Martín López, Juan (Date of defense: 2022-07-15)
The present Thesis is divided in three chapters: 1. Design and synthesis of new soluble epoxide hydrolase inhibitors (sEHI) The synthesis of new soluble epoxide hydrolase inhibitors based on ureas ...
Alcalde Alvites, Miguel Angel (Date of defense: 2023-12-19)
[eng] Plant biofactories constitute an eco-friendly alternative to chemical synthesis as they have a lower environmental impact and therefore contribute to a more sustainable future. Hairy root cultures, ...
Schmitz, Claus-A. (Date of defense: 2023-04-26)
[eng] We investigated the structure function relationship of PorX by combined biophysical experiments and enzymatic assays. As a regulator of the type 9 secretion system (T9SS) of the human pathogen ...
Pérez Matas, Edgar (Date of defense: 2023-12-19)
[eng] Plant specialized metabolism is the source of a wide range of bioactive compounds, some of which with relevant pharmacological properties. Nowadays, cancer is one of the main causes of mortality ...
Sortino, Rosalba (Date of defense: 2023-10-18)
[eng] G protein-coupled receptors (GPCRs) modulate diverse cellular responses to the majority of neurotransmitters and hormones within the human body. They exhibit much structural and functional diversity ...
Lovera Ulecia, Marta (Date of defense: 2023-05-05)
[eng] Cohen syndrome (CS) is an ultra-rare, multi-system, autosomal recessive disorder caused by mutations in the VPS13B gene on chromosome 8q22.2. The most characteristic clinical features of this ...