Cano Fernández, Amanda (Date of defense: 2018-11-09)
Las enfermedades del sistema nervioso central (SNC) engloban a un conjunto de patologías de elevada gravedad debido a la importancia de este sistema para el organismo. La Epilepsia del Lóbulo Temporal ...
Morcelle Magaña, Carmen (Date of defense: 2017-09-19)
In most human cancers, the c-Myc transcription factor is deregulated and/or its levels are elevated, particularly in colorectal cancer (CRC). Earlier studies suggested a direct relationship between ...
Sotillo Rodríguez, Fernando (Date of defense: 2018-02-16)
Lysinuric Protein Intolerance (LPI, MIM #222700) is a rare autosomic disease caused by mutations in SLC7A7 gene. Hallmarks of LPI are malabsorption and deficient renal reabsorption of cationic amino ...
Cañadas Enrich, Cristina (Date of defense: 2018-11-28)
El presente trabajo de investigación versa sobre la caracterización in vitro, ex vivo e in vivo de dos sistemas nanoestructurados de liberación sostenida (PF-F1NPs y PF- F2NPs) conteniendo pranoprofeno ...
Baelo Álvarez, Aida (Date of defense: 2021-01-28)
Bacterial infections are a major health concern worldwide due to the mortality and comorbidity associated levels. Besides the development of drug-resistance mechanisms, most recalcitrant infections are ...
Giraldo Clemente, Sandra (Date of defense: 2021-02-26)
Les proteïnes motores s’encarreguen del transport intracel·lular de cargoes a través de fibres tubulars presents en el citosquelet mitjançant la hidròlisis del trifosfat d'adenosina (ATP) com a força ...
Farrera Sal, Martí (Date of defense: 2020-10-30)
The oncolytic viruses (OVs) preferentially infect tumor and selectively replicate in cancer cells without harming normal tissues. OVs have been tested in clinical trials as monotherapy or combined with ...
Vivas Pradillo, Daniel (Date of defense: 2018-12-14)
Bone is a highly organised and specialised connective tissue that provides a rigid, protective and supporting framework to the body. In addition to this, bone is unique in its capacity to self-regenerate ...
Medina Vives, Jordi (Date of defense: 2018-02-12)
The common scope of this thesis is the application of structural biology and biophysics to obtain novel data on nuclear proteins that modulate DNA transcription. The proper regulation and functioning ...
Rubio Canalejas, Alba (Date of defense: 2023-07-07)
[spa] Las ribonucleótido reductasas (RNR) son enzimas esenciales que convierten los ribonucleótidos en desoxirribonucleótidos, los monómeros utilizados en la síntesis y reparación del ADN. Existen ...