Ara mostrant els elements 1-10 de 42
Aledavood, Elnaz (Data de defensa: 2021-10-01)
This doctoral thesis is focused on disclosing molecular factors that regulate the functional mechanism of key targets in i) metabolic disorders, such as diabetes and obesity, and ii) tuberculosis (TB). ...
Pascual Gilabert, Marta (Data de defensa: 2022-11-04)
[eng] Myotonic dystrophy type 1 (DM1), one of the more complex diseases already known, is the most common and multisystemic rare neuromuscular disease among adults, without cure and limited pharmacological ...
Liu, Changxin (Data de defensa: 2020-10-29)
The main topic of this Thesis is to investigate the contribution of polyamines to defense in Arabidopsis thaliana and the requirement of callose deposition for full expression of effector-triggered ...
Vilaplana Saiz, Marta (Data de defensa: 2021-01-22)
This thesis shows the research carried out on two specific diseases: familial hypercholesterolemia, which is included within the cardiovascular diseases group, and cancer. These diseases are the major ...
Petrillo, Giovanna (Data de defensa: 2017-06-28)
The rapid progress in structural and molecular biology over the past fifteen years has allowed chemists to access the structures of enzymes, of their complexes and of engineered variants. This wealth ...
González Velasco, Lorena (Data de defensa: 2021-09-14)
Non-canonical activation of p38α MAPK has been associated to cardiomyocyte death in several cardiovascular pathologies, such as myocardial ischaemia-reper- fusion injury. Unfortunately, current p38α ...
Suñé Pou, Marc (Data de defensa: 2019-07-12)
Cationic Solid Lipid Nanoparticles (cSLNs) are one of the most promising nonviral vectors for gene therapy and DNA / RNA delivery. The aim of this thesis is the development and research of new formulations ...
Bustos Salgado, Paola (Data de defensa: 2021-06-22)
This research work was aimed at the characterization in vitro, ex vivo and in vivo of nanostructured systems which independently contain a natural flavanone extracted from Eysenhardtia platycarpa and ...
Novak, Ana (Data de defensa: 2019-06-26)
Parenteral nutrition-associated liver dysfunction (PNALD) is one of the most severe long-term parenteral nutrition complications, which was attributed to the phytosterols, found in vegetable oil based ...
Hidalgo Martínez, Diego Alberto (Data de defensa: 2017-07-10)
The thesis is presented as a compendium of publications and includes six different sections: General Introduction, Objectives, Results, General Discussion, Conclusions and References. The General ...