Aledavood, Elnaz (Date of defense: 2021-10-01)
This doctoral thesis is focused on disclosing molecular factors that regulate the functional mechanism of key targets in i) metabolic disorders, such as diabetes and obesity, and ii) tuberculosis (TB). ...
Bofill Herrera, Lidia (Date of defense: 2021-09-13)
La salut ha estat sempre una de les principals preocupacions de la societat, i més encara amb la situació de pandèmia actual produïda pel virus (SARS-CoV-2) s’és conscient de que portar un estil de vida ...
Avalos de León, Cindy Guadalupe (Date of defense: 2020-07-21)
Cada año, miles de personas fallecen a causa de enfermedades hepáticas en estado terminal, siendo la falta de injertos hepáticos un problema sin resolver en la práctica clínica. Para tratar de resolver ...
Bustos Salgado, Paola (Date of defense: 2021-06-22)
This research work was aimed at the characterization in vitro, ex vivo and in vivo of nanostructured systems which independently contain a natural flavanone extracted from Eysenhardtia platycarpa and ...
Bujaldon Ormaechea, Esther (Date of defense: 2019-10-04)
La hepatectomía parcial bajo isquemia-reperfusión (PH + I/R) es una estrategia que se utiliza comúnmente en la práctica clínica para reducir la hemorragia durante la resección del parénquima hepático. ...
González Díez, Aleix (Date of defense: 2023-07-24)
[eng] G protein-coupled-receptors (GPCRs) are the largest family of membrane proteins and mediate important cellular responses. Metabotropic glutamate receptors (mGlu) belong to the Glutamate family/Class ...
Giraldo Clemente, Sandra (Date of defense: 2021-02-26)
Les proteïnes motores s’encarreguen del transport intracel·lular de cargoes a través de fibres tubulars presents en el citosquelet mitjançant la hidròlisis del trifosfat d'adenosina (ATP) com a força ...
Jora, Beatrice Elena (Date of defense: 2022-10-27)
[eng] The present thesis focuses on the study and synthesis of three active principles (APIs) with therapeutic activity. Although these compounds are commercially available, their route of synthesis are ...
Duran Corbera, Anna (Date of defense: 2022-04-22)
G protein-coupled receptors (GPCRs) are a large family of membrane proteins responsible for signaling transduction processes. Due to their roles in modulating essential physiological functions, GPCRs ...
Martín López, Juan (Date of defense: 2022-07-15)
The present Thesis is divided in three chapters: 1. Design and synthesis of new soluble epoxide hydrolase inhibitors (sEHI) The synthesis of new soluble epoxide hydrolase inhibitors based on ureas ...