dc.contributor
Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut
dc.contributor.author
Ferrando-Bernal, Manuel
dc.date.accessioned
2021-09-27T16:11:41Z
dc.date.available
2021-09-27T16:11:41Z
dc.date.issued
2021-07-09
dc.identifier.uri
http://hdl.handle.net/10803/672475
dc.description.abstract
The aim of this thesis is to apply Identity by Descent (IBD) methodology to identify ancestry connections among individuals from genetically similar populations. Recombination events diminish the likelihood to detect IBDs. As most of the aDNA samples date from 2,000 years ago or more, this methodology has rarely been applied to these studies. In this thesis we detect IBD among modern individuals from similar Bantu populations and among modern Europeans with an historical individual (700 years ago) from the Iberian peninsula, which was sequenced to a high coverage. Our results show that IBDs can be used to detect the genomic structure in genetically close populations. For example, they can be used to show high degrees of endogamy caused by isolation or to identify ancestral connections among individuals belonging to different populations that otherwise would be difficult to see with other more commonly used methods.
dc.format.mimetype
application/pdf
dc.rights.license
L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de
les condicions d'ús establertes per la següent llicència Creative Commons:
http://creativecommons.org/licenses/by/4.0/
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
*
dc.source
TDX (Tesis Doctorals en Xarxa)
dc.subject
Identity-by-Descent
dc.subject
Networks Spanish
dc.subject
Idéntico por descendencia
dc.title
Analysis of co-ancestry links in modern and ancient human populations
dc.type
info:eu-repo/semantics/doctoralThesis
dc.type
info:eu-repo/semantics/publishedVersion
dc.contributor.authoremail
manu.ferrandobernal@gmail.com
dc.contributor.director
Lalueza Fox, Carles
dc.rights.accessLevel
info:eu-repo/semantics/openAccess
dc.description.degree
Programa de doctorat en Biomedicina